STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYT17Synaptotagmin-17; Plays a role in dendrite formation by melanocytes. Belongs to the synaptotagmin family. (473 aa)    
Predicted Functional Partners:
CHMP4A
CHMP4A isoform 4.
    
   0.751
CLEC19A
C-type lectin domain containing 19A.
 
 
 
 0.706
ITSN2
ITSN2 isoform 3.
     
 0.598
STON2
STON2 isoform 2; Belongs to the Stoned B family.
  
 0.565
AGBL4
AGBL4 isoform 1.
      
 0.560
RIMS2
Regulating synaptic membrane exocytosis 2.
     
0.522
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.491
MID2
MID2 isoform 2.
    
  0.451
ITSN1
ITSN1 isoform 4.
     
 0.450
CR201_G0042289
SAXO2 isoform 8.
  
 
  0.410
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.