node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BOLA1 | BOLA2B | ENSPPYP00000001068 | ENSPPYP00000008182 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | 0.838 |
BOLA1 | BOLA3 | ENSPPYP00000001068 | ENSPPYP00000013699 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | BolA family member 3; Belongs to the BolA/IbaG family. | 0.936 |
BOLA1 | CIAPIN1 | ENSPPYP00000001068 | ENSPPYP00000008347 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.913 |
BOLA1 | ENSPPYP00000018104 | ENSPPYP00000001068 | ENSPPYP00000018104 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | annotation not available | 0.771 |
BOLA1 | GLRX3 | ENSPPYP00000001068 | ENSPPYP00000003233 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | GLRX3 isoform 1. | 0.955 |
BOLA1 | GLRX5 | ENSPPYP00000001068 | ENSPPYP00000006952 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | GLRX5 isoform 2. | 0.962 |
BOLA1 | NDUFA6 | ENSPPYP00000001068 | ENSPPYP00000013269 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. | 0.407 |
BOLA1 | TIMM10B | ENSPPYP00000001068 | ENSPPYP00000004060 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | Mitochondrial import inner membrane translocase subunit Tim10 B; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. | 0.486 |
BOLA2B | BOLA1 | ENSPPYP00000008182 | ENSPPYP00000001068 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | 0.838 |
BOLA2B | BOLA3 | ENSPPYP00000008182 | ENSPPYP00000013699 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | BolA family member 3; Belongs to the BolA/IbaG family. | 0.473 |
BOLA2B | CIAPIN1 | ENSPPYP00000008182 | ENSPPYP00000008347 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.639 |
BOLA2B | ENSPPYP00000018104 | ENSPPYP00000008182 | ENSPPYP00000018104 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | annotation not available | 0.846 |
BOLA2B | GLRX3 | ENSPPYP00000008182 | ENSPPYP00000003233 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | GLRX3 isoform 1. | 0.904 |
BOLA2B | GLRX5 | ENSPPYP00000008182 | ENSPPYP00000006952 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | GLRX5 isoform 2. | 0.555 |
BOLA2B | GPR89A | ENSPPYP00000008182 | ENSPPYP00000001093 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | GPR89A isoform 1. | 0.504 |
BOLA2B | NDUFA2 | ENSPPYP00000008182 | ENSPPYP00000017734 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.426 |
BOLA2B | NDUFA6 | ENSPPYP00000008182 | ENSPPYP00000013269 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. | 0.514 |
BOLA2B | TIMM10B | ENSPPYP00000008182 | ENSPPYP00000004060 | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | Mitochondrial import inner membrane translocase subunit Tim10 B; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. | 0.429 |
BOLA3 | BOLA1 | ENSPPYP00000013699 | ENSPPYP00000001068 | BolA family member 3; Belongs to the BolA/IbaG family. | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | 0.936 |
BOLA3 | BOLA2B | ENSPPYP00000013699 | ENSPPYP00000008182 | BolA family member 3; Belongs to the BolA/IbaG family. | BOLA2-SMG1P6 isoform 3; Belongs to the BolA/IbaG family. | 0.473 |