STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MT2AMetallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. (61 aa)    
Predicted Functional Partners:
GLRX
GLRX isoform 1.
   
  
 0.606
VNN2
VNN2 isoform 1.
      
 0.581
SULT1C2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.580
MT1X
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
  
   
0.533
ENO1
Alpha-enolase; Glycolytic enzyme the catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production; Belongs to the enolase family.
      
 0.520
RECQL4
RECQL4 isoform 2.
      
 0.520
MT1B
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
  
 
0.449
LOC100936088
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
  
 
0.448
CR201_G0014586
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
  
 
0.448
LOC100435295
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
  
 
0.447
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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