STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100441148SERPINB4 isoform 1; Belongs to the serpin family. (390 aa)    
Predicted Functional Partners:
CTSG
CTSG isoform 1; Belongs to the peptidase S1 family.
    
 0.940
SERPINB13
Serpin family B member 13; Belongs to the serpin family.
  
   
0.739
CTSS
CTSS isoform 1; Belongs to the peptidase C1 family.
    
 0.639
F2
Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
   
 0.598
SNX27
SNX27 isoform 2.
      
 0.574
CTSL
CTSL isoform 2; Belongs to the peptidase C1 family.
   
 0.570
CYTIP
CYTIP isoform 4.
   
  
 0.566
KLK5
KLK5 isoform 1; Belongs to the peptidase S1 family.
   
 0.513
CTRL
CTRL isoform 2; Belongs to the peptidase S1 family.
    
 0.498
CSTA
CSTA isoform 1; Belongs to the cystatin family.
   
 0.498
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.