STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNN2Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). (309 aa)    
Predicted Functional Partners:
WDR90
WDR90 isoform 5.
    
 
 0.685
GAS2
Growth arrest specific 2.
      
 0.627
ASPM
ASPM isoform 2.
   
  
 0.563
VCL
VCL isoform 2.
   
 
 0.531
WDR1
WDR1 isoform 1.
   
 
 0.522
ENKUR
ENKUR isoform 2.
   
 
 0.517
ZYX
ZYX isoform 1.
   
 
 0.504
UTRN
UTRN isoform 2.
      
 0.503
ZBTB37
ZBTB37 isoform 2.
      
 0.497
CALML4
LOW QUALITY PROTEIN: calmodulin-like protein 4.
   
 0.484
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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