STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELMO2Engulfment and cell motility protein 2; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity). (720 aa)    
Predicted Functional Partners:
DOCK1
DOCK1 isoform 1; Belongs to the DOCK family.
    
 0.997
RHOG
Ras homolog family member G.
    
 0.997
ELMO1
ELMO1 isoform 1.
  
 
 
0.990
CRK
CRK isoform 1.
    
 0.975
ELMO3
ELMO3 isoform 2.
  
 
 
0.974
DOCK4
DOCK4 isoform 1; Belongs to the DOCK family.
    
 0.962
ADGRB1
ADGRB1 isoform 2.
   
 
 0.959
CRKL
CRKL isoform 1.
    
 0.959
RAC2
Rac family small GTPase 2.
    
 0.953
RAC3
RAC3 isoform 1.
    
 0.948
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.