node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEPT1 | MBOAT2 | ENSPPYP00000001209 | ENSPPYP00000014144 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | 0.925 |
CEPT1 | PEMT | ENSPPYP00000001209 | ENSPPYP00000009034 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | 0.950 |
CEPT1 | PISD | ENSPPYP00000001209 | ENSPPYP00000013093 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. | 0.940 |
CEPT1 | PLA2G4A | ENSPPYP00000001209 | ENSPPYP00000000461 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). | 0.913 |
CEPT1 | PLD1 | ENSPPYP00000001209 | ENSPPYP00000015981 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.930 |
CEPT1 | PLD2 | ENSPPYP00000001209 | ENSPPYP00000008833 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phospholipase. | 0.930 |
CEPT1 | PTDSS2 | ENSPPYP00000001209 | ENSPPYP00000003331 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine synthase 2. | 0.947 |
CEPT1 | SELENOI | ENSPPYP00000001209 | ENSPPYP00000014048 | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Ethanolaminephosphotransferase 1; Catalyzes phosphatidylethanolamine biosynthesis from CDP- ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via 'Kennedy' pathway (By similarity). | 0.966 |
CRLS1 | PISD | ENSPPYP00000011954 | ENSPPYP00000013093 | CRLS1 isoform 1. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. | 0.922 |
MBOAT2 | CEPT1 | ENSPPYP00000014144 | ENSPPYP00000001209 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.925 |
MBOAT2 | PEMT | ENSPPYP00000014144 | ENSPPYP00000009034 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | 0.928 |
MBOAT2 | PISD | ENSPPYP00000014144 | ENSPPYP00000013093 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. | 0.938 |
MBOAT2 | PLA1A | ENSPPYP00000014144 | ENSPPYP00000015111 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phospholipase A1 member A; Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production (By similarity). | 0.905 |
MBOAT2 | PLD1 | ENSPPYP00000014144 | ENSPPYP00000015981 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phospholipase. | 0.922 |
MBOAT2 | PLD2 | ENSPPYP00000014144 | ENSPPYP00000008833 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phospholipase. | 0.922 |
MBOAT2 | PTDSS2 | ENSPPYP00000014144 | ENSPPYP00000003331 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Phosphatidylserine synthase 2. | 0.925 |
MBOAT2 | SELENOI | ENSPPYP00000014144 | ENSPPYP00000014048 | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | Ethanolaminephosphotransferase 1; Catalyzes phosphatidylethanolamine biosynthesis from CDP- ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via 'Kennedy' pathway (By similarity). | 0.924 |
PEMT | CEPT1 | ENSPPYP00000009034 | ENSPPYP00000001209 | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.950 |
PEMT | MBOAT2 | ENSPPYP00000009034 | ENSPPYP00000014144 | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | MBOAT2 isoform 1; Belongs to the membrane-bound acyltransferase family. | 0.928 |
PEMT | PISD | ENSPPYP00000009034 | ENSPPYP00000013093 | Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. | 0.952 |