node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARNTL | ARNTL2 | ENSPPYP00000003988 | ENSPPYP00000005000 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Aryl hydrocarbon receptor nuclear translocator like 2. | 0.667 |
ARNTL | CLOCK | ENSPPYP00000003988 | ENSPPYP00000016487 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Circadian locomoter output cycles protein kaput; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, [...] | 0.978 |
ARNTL | CRY1 | ENSPPYP00000003988 | ENSPPYP00000005604 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Cryptochrome circadian regulator 1. | 0.995 |
ARNTL | CRY2 | ENSPPYP00000003988 | ENSPPYP00000003822 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Cryptochrome circadian regulator 2. | 0.995 |
ARNTL | CSNK1D | ENSPPYP00000003988 | ENSPPYP00000009846 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.975 |
ARNTL | LOC100447547 | ENSPPYP00000003988 | ENSPPYP00000013183 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | T0085674 isoform 1; Belongs to the protein kinase superfamily. | 0.967 |
ARNTL | NPAS2 | ENSPPYP00000003988 | ENSPPYP00000013492 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | NPAS2 isoform 1. | 0.957 |
ARNTL | NR1D1 | ENSPPYP00000003988 | ENSPPYP00000009517 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | NR1D1 isoform 1. | 0.607 |
ARNTL | PER2 | ENSPPYP00000003988 | ENSPPYP00000014901 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | PER2 isoform 2. | 0.969 |
ARNTL | RORA | ENSPPYP00000003988 | ENSPPYP00000007402 | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | RORA isoform 12. | 0.577 |
ARNTL2 | ARNTL | ENSPPYP00000005000 | ENSPPYP00000003988 | Aryl hydrocarbon receptor nuclear translocator like 2. | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | 0.667 |
ARNTL2 | CLOCK | ENSPPYP00000005000 | ENSPPYP00000016487 | Aryl hydrocarbon receptor nuclear translocator like 2. | Circadian locomoter output cycles protein kaput; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, [...] | 0.996 |
ARNTL2 | CRY1 | ENSPPYP00000005000 | ENSPPYP00000005604 | Aryl hydrocarbon receptor nuclear translocator like 2. | Cryptochrome circadian regulator 1. | 0.824 |
ARNTL2 | CRY2 | ENSPPYP00000005000 | ENSPPYP00000003822 | Aryl hydrocarbon receptor nuclear translocator like 2. | Cryptochrome circadian regulator 2. | 0.827 |
ARNTL2 | CSNK1D | ENSPPYP00000005000 | ENSPPYP00000009846 | Aryl hydrocarbon receptor nuclear translocator like 2. | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] | 0.749 |
ARNTL2 | LOC100447547 | ENSPPYP00000005000 | ENSPPYP00000013183 | Aryl hydrocarbon receptor nuclear translocator like 2. | T0085674 isoform 1; Belongs to the protein kinase superfamily. | 0.735 |
ARNTL2 | NPAS2 | ENSPPYP00000005000 | ENSPPYP00000013492 | Aryl hydrocarbon receptor nuclear translocator like 2. | NPAS2 isoform 1. | 0.978 |
ARNTL2 | NR1D1 | ENSPPYP00000005000 | ENSPPYP00000009517 | Aryl hydrocarbon receptor nuclear translocator like 2. | NR1D1 isoform 1. | 0.622 |
ARNTL2 | PER2 | ENSPPYP00000005000 | ENSPPYP00000014901 | Aryl hydrocarbon receptor nuclear translocator like 2. | PER2 isoform 2. | 0.762 |
ARNTL2 | RORA | ENSPPYP00000005000 | ENSPPYP00000007402 | Aryl hydrocarbon receptor nuclear translocator like 2. | RORA isoform 12. | 0.535 |