Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD45 | CALR | ENSPPYP00000000575 | ENSPPYP00000010780 | ANKRD45 isoform 1. | Calreticulin. | 0.786 |
ANKRD45 | CANX | ENSPPYP00000000575 | ENSPPYP00000018041 | ANKRD45 isoform 1. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | 0.787 |
ANKRD45 | DNAJC10 | ENSPPYP00000000575 | ENSPPYP00000014516 | ANKRD45 isoform 1. | DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, [...] | 0.939 |
ANKRD45 | ENSPPYP00000001345 | ENSPPYP00000000575 | ENSPPYP00000001345 | ANKRD45 isoform 1. | annotation not available | 0.860 |
ANKRD45 | GAK | ENSPPYP00000000575 | ENSPPYP00000016219 | ANKRD45 isoform 1. | GAK isoform 7. | 0.762 |
ANKRD45 | HSP90B1 | ENSPPYP00000000575 | ENSPPYP00000023483 | ANKRD45 isoform 1. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | 0.860 |
ANKRD45 | HSPA4 | ENSPPYP00000000575 | ENSPPYP00000017643 | ANKRD45 isoform 1. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.622 |
ANKRD45 | HYOU1 | ENSPPYP00000000575 | ENSPPYP00000004526 | ANKRD45 isoform 1. | Hypoxia up-regulated 1. | 0.932 |
CALR | ANKRD45 | ENSPPYP00000010780 | ENSPPYP00000000575 | Calreticulin. | ANKRD45 isoform 1. | 0.786 |
CALR | CANX | ENSPPYP00000010780 | ENSPPYP00000018041 | Calreticulin. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | 0.992 |
CALR | DNAJC10 | ENSPPYP00000010780 | ENSPPYP00000014516 | Calreticulin. | DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, [...] | 0.823 |
CALR | EDEM1 | ENSPPYP00000010780 | ENSPPYP00000015312 | Calreticulin. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.687 |
CALR | ENSPPYP00000001345 | ENSPPYP00000010780 | ENSPPYP00000001345 | Calreticulin. | annotation not available | 0.930 |
CALR | HSP90B1 | ENSPPYP00000010780 | ENSPPYP00000023483 | Calreticulin. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Belongs to the heat shock protein 90 family. | 0.990 |
CALR | HSPA4 | ENSPPYP00000010780 | ENSPPYP00000017643 | Calreticulin. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.770 |
CALR | HSPA5 | ENSPPYP00000010780 | ENSPPYP00000021973 | Calreticulin. | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 0.952 |
CALR | HYOU1 | ENSPPYP00000010780 | ENSPPYP00000004526 | Calreticulin. | Hypoxia up-regulated 1. | 0.847 |
CANX | ANKRD45 | ENSPPYP00000018041 | ENSPPYP00000000575 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | ANKRD45 isoform 1. | 0.787 |
CANX | CALR | ENSPPYP00000018041 | ENSPPYP00000010780 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | Calreticulin. | 0.992 |
CANX | DNAJC10 | ENSPPYP00000018041 | ENSPPYP00000014516 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at t [...] | DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, [...] | 0.780 |
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