node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DNAJC24 | DPH1 | ENSPPYP00000003892 | ENSPPYP00000008774 | DnaJ heat shock protein family (Hsp40) member C24. | DPH1 isoform 1. | 0.672 |
DNAJC24 | DPH2 | ENSPPYP00000003892 | ENSPPYP00000001667 | DnaJ heat shock protein family (Hsp40) member C24. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | 0.712 |
DNAJC24 | DPH3 | ENSPPYP00000003892 | ENSPPYP00000015754 | DnaJ heat shock protein family (Hsp40) member C24. | DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). | 0.685 |
DNAJC24 | DPH5 | ENSPPYP00000003892 | ENSPPYP00000001285 | DnaJ heat shock protein family (Hsp40) member C24. | Diphthamide biosynthesis 5. | 0.589 |
DNAJC24 | EEF2 | ENSPPYP00000003892 | ENSPPYP00000010534 | DnaJ heat shock protein family (Hsp40) member C24. | Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] | 0.850 |
DPH1 | DNAJC24 | ENSPPYP00000008774 | ENSPPYP00000003892 | DPH1 isoform 1. | DnaJ heat shock protein family (Hsp40) member C24. | 0.672 |
DPH1 | DPH2 | ENSPPYP00000008774 | ENSPPYP00000001667 | DPH1 isoform 1. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | 0.991 |
DPH1 | DPH3 | ENSPPYP00000008774 | ENSPPYP00000015754 | DPH1 isoform 1. | DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). | 0.982 |
DPH1 | DPH5 | ENSPPYP00000008774 | ENSPPYP00000001285 | DPH1 isoform 1. | Diphthamide biosynthesis 5. | 0.971 |
DPH1 | EEF2 | ENSPPYP00000008774 | ENSPPYP00000010534 | DPH1 isoform 1. | Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] | 0.917 |
DPH1 | EFL1 | ENSPPYP00000008774 | ENSPPYP00000007632 | DPH1 isoform 1. | EFL1 isoform 1. | 0.691 |
DPH1 | ELP3 | ENSPPYP00000008774 | ENSPPYP00000024709 | DPH1 isoform 1. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.582 |
DPH2 | DNAJC24 | ENSPPYP00000001667 | ENSPPYP00000003892 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | DnaJ heat shock protein family (Hsp40) member C24. | 0.712 |
DPH2 | DPH1 | ENSPPYP00000001667 | ENSPPYP00000008774 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | DPH1 isoform 1. | 0.991 |
DPH2 | DPH3 | ENSPPYP00000001667 | ENSPPYP00000015754 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). | 0.984 |
DPH2 | DPH5 | ENSPPYP00000001667 | ENSPPYP00000001285 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | Diphthamide biosynthesis 5. | 0.972 |
DPH2 | EEF2 | ENSPPYP00000001667 | ENSPPYP00000010534 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] | 0.919 |
DPH2 | EFL1 | ENSPPYP00000001667 | ENSPPYP00000007632 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | EFL1 isoform 1. | 0.691 |
DPH2 | ELP3 | ENSPPYP00000001667 | ENSPPYP00000024709 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2); Belongs to the DPH1/DPH2 family. DPH2 subfamily. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.482 |
DPH3 | DNAJC24 | ENSPPYP00000015754 | ENSPPYP00000003892 | DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta). | DnaJ heat shock protein family (Hsp40) member C24. | 0.685 |