node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BORA | CEP70 | ENSPPYP00000006164 | ENSPPYP00000015824 | BORA aurora kinase A activator. | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | 0.531 |
BORA | HAUS5 | ENSPPYP00000006164 | ENSPPYP00000011050 | BORA aurora kinase A activator. | HAUS5 isoform 5. | 0.463 |
BORA | PLK1 | ENSPPYP00000006164 | ENSPPYP00000008136 | BORA aurora kinase A activator. | Serine/threonine-protein kinase PLK. | 0.995 |
BORA | PLK4 | ENSPPYP00000006164 | ENSPPYP00000016820 | BORA aurora kinase A activator. | Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...] | 0.698 |
CD19 | CD33 | ENSPPYP00000008166 | ENSPPYP00000011550 | CD19 isoform 3. | CD33 isoform 3. | 0.708 |
CD19 | CEP70 | ENSPPYP00000008166 | ENSPPYP00000015824 | CD19 isoform 3. | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | 0.814 |
CD19 | TNFRSF17 | ENSPPYP00000008166 | ENSPPYP00000008044 | CD19 isoform 3. | TNFRSF17 isoform 1. | 0.558 |
CD33 | CD19 | ENSPPYP00000011550 | ENSPPYP00000008166 | CD33 isoform 3. | CD19 isoform 3. | 0.708 |
CD33 | CEP70 | ENSPPYP00000011550 | ENSPPYP00000015824 | CD33 isoform 3. | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | 0.562 |
CEP70 | BORA | ENSPPYP00000015824 | ENSPPYP00000006164 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | BORA aurora kinase A activator. | 0.531 |
CEP70 | CD19 | ENSPPYP00000015824 | ENSPPYP00000008166 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | CD19 isoform 3. | 0.814 |
CEP70 | CD33 | ENSPPYP00000015824 | ENSPPYP00000011550 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | CD33 isoform 3. | 0.562 |
CEP70 | EGFR | ENSPPYP00000015824 | ENSPPYP00000019671 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | Receptor protein-tyrosine kinase. | 0.497 |
CEP70 | FOLH1 | ENSPPYP00000015824 | ENSPPYP00000004301 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | FOLH1 isoform 3. | 0.557 |
CEP70 | HAUS5 | ENSPPYP00000015824 | ENSPPYP00000011050 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | HAUS5 isoform 5. | 0.492 |
CEP70 | PLK1 | ENSPPYP00000015824 | ENSPPYP00000008136 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | Serine/threonine-protein kinase PLK. | 0.889 |
CEP70 | PLK4 | ENSPPYP00000015824 | ENSPPYP00000016820 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...] | 0.484 |
CEP70 | RAB3IP | ENSPPYP00000015824 | ENSPPYP00000005426 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | T0046992 isoform 1. | 0.499 |
CEP70 | TNFRSF17 | ENSPPYP00000015824 | ENSPPYP00000008044 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | TNFRSF17 isoform 1. | 0.502 |
EGFR | CEP70 | ENSPPYP00000019671 | ENSPPYP00000015824 | Receptor protein-tyrosine kinase. | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). | 0.497 |