STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFF1AFF1 isoform 1. (1184 aa)    
Predicted Functional Partners:
MLLT1
MLLT1 isoform 1.
    
 0.998
MLLT3
MLLT3 isoform 1.
    
 0.998
CR201_G0027625
CDK9 isoform 1; Belongs to the protein kinase superfamily.
    
 0.990
ELL3
ELL3 isoform 1.
   
 0.982
EAF1
ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
    
 0.982
CCNT1
CCNT1 isoform 2; Belongs to the cyclin family.
   
 0.980
ELL2
Elongation factor for RNA polymerase II 2.
   
 0.920
AFF4
AF4/FMR2 family member 4.
    
0.907
CCNT2
CCNT2 isoform 2; Belongs to the cyclin family.
   
 0.889
ENSPPYP00000000794
annotation not available
   
 0.881
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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