node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CR201_G0037179 | EFTUD2 | ENSPPYP00000010397 | ENSPPYP00000009352 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.995 |
CR201_G0037179 | IK | ENSPPYP00000010397 | ENSPPYP00000017737 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Protein Red; Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. | 0.980 |
CR201_G0037179 | LSM8 | ENSPPYP00000010397 | ENSPPYP00000024548 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.912 |
CR201_G0037179 | MFAP1 | ENSPPYP00000010397 | ENSPPYP00000007283 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | MFAP1 isoform 1. | 0.981 |
CR201_G0037179 | PRPF38A | ENSPPYP00000010397 | ENSPPYP00000001567 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.985 |
CR201_G0037179 | PRPF6 | ENSPPYP00000010397 | ENSPPYP00000012574 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Pre-mRNA-processing factor 6; Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. | 0.999 |
CR201_G0037179 | SF3B3 | ENSPPYP00000010397 | ENSPPYP00000008511 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] | 0.851 |
CR201_G0037179 | SMU1 | ENSPPYP00000010397 | ENSPPYP00000021445 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | WD_REPEATS_REGION domain-containing protein. | 0.980 |
CR201_G0037179 | WBP4 | ENSPPYP00000010397 | ENSPPYP00000006048 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | WW domain binding protein 4. | 0.980 |
CR201_G0037179 | ZMAT2 | ENSPPYP00000010397 | ENSPPYP00000017746 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | Zinc finger matrin-type 2. | 0.985 |
EFTUD2 | CR201_G0037179 | ENSPPYP00000009352 | ENSPPYP00000010397 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. | 0.995 |
EFTUD2 | IK | ENSPPYP00000009352 | ENSPPYP00000017737 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Protein Red; Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. | 0.968 |
EFTUD2 | LSM8 | ENSPPYP00000009352 | ENSPPYP00000024548 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.981 |
EFTUD2 | MFAP1 | ENSPPYP00000009352 | ENSPPYP00000007283 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | MFAP1 isoform 1. | 0.926 |
EFTUD2 | PRPF38A | ENSPPYP00000009352 | ENSPPYP00000001567 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.951 |
EFTUD2 | PRPF6 | ENSPPYP00000009352 | ENSPPYP00000012574 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Pre-mRNA-processing factor 6; Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. | 0.999 |
EFTUD2 | SF3B3 | ENSPPYP00000009352 | ENSPPYP00000008511 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...] | 0.990 |
EFTUD2 | SMU1 | ENSPPYP00000009352 | ENSPPYP00000021445 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | WD_REPEATS_REGION domain-containing protein. | 0.924 |
EFTUD2 | WBP4 | ENSPPYP00000009352 | ENSPPYP00000006048 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | WW domain binding protein 4. | 0.916 |
EFTUD2 | ZMAT2 | ENSPPYP00000009352 | ENSPPYP00000017746 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | Zinc finger matrin-type 2. | 0.926 |