STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)    
Predicted Functional Partners:
MAPK14
Mitogen-activated protein kinase.
   
 0.992
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.991
MAPK1
Mitogen-activated protein kinase 1 isoform X1.
   
 0.985
MAPK8
Mitogen-activated protein kinase.
   
 0.978
MAPK10
Mitogen-activated protein kinase.
   
 0.954
MAPK12
Mitogen-activated protein kinase.
   
 0.951
MAPK9
Mitogen-activated protein kinase.
   
 0.951
MAPK13
Mitogen-activated protein kinase.
   
 0.950
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
 
 0.908
ZFP36
ZFP36 isoform 1.
   
 
 0.874
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.