STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRS2Magnesium transporter MRS2 homolog, mitochondrial; Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix. Required for normal expression of the mitochondrial respiratory complex I subunits. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (381 aa)    
Predicted Functional Partners:
CBS
Cystathionine beta-synthase isoform X1.
      
 0.672
PANX1
Pannexin-1; Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis; Belongs to the pannexin family.
      
 0.580
SLC41A1
Solute carrier family 41 member 1; Acts as a magnesium transporter that is responsive to magnesium balance; Belongs to the SLC41A transporter family.
      
 0.551
SLC41A3
SLC41A3 isoform 1.
      
 0.463
SLC41A2
Solute carrier family 41 member 2.
      
 0.456
ENSPPYP00000018409
annotation not available
      
 0.433
CNNM2
CNNM2 isoform 1.
      
 0.420
CR201_G0023344
PLEKHB1 isoform 4.
      
 0.420
CR201_G0029377
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.400
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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