STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABT1Activator of basal transcription 1; Coud be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity). (272 aa)    
Predicted Functional Partners:
RRP36
RRP36 isoform 1.
   
 
 0.976
DDX49
DEAD-box helicase 49; Belongs to the DEAD box helicase family.
   
 
 0.970
ESF1
ESF1 nucleolar pre-rRNA processing protein homolog.
   
 
 0.957
BYSL
BYSL isoform 1.
   
 
 0.952
KRR1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.946
DDX10
RNA helicase.
   
 
 0.943
UTP25
UTP25 small subunit processor component.
   
 
 0.942
NOP14
NOP14 nucleolar protein.
   
 
 0.934
DHX15
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns (By similarity). Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
   
 
 0.922
UTP6
UTP6 isoform 1.
   
 
 0.920
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.