node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AASDH | ALAD | ENSPPYP00000016479 | ENSPPYP00000021874 | Aminoadipate-semialdehyde dehydrogenase. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.867 |
AASDH | FASN | ENSPPYP00000016479 | ENSPPYP00000009843 | Aminoadipate-semialdehyde dehydrogenase. | FASN isoform 1. | 0.976 |
ALAD | AASDH | ENSPPYP00000021874 | ENSPPYP00000016479 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Aminoadipate-semialdehyde dehydrogenase. | 0.867 |
ALAD | ALAS1 | ENSPPYP00000021874 | ENSPPYP00000015461 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.977 |
ALAD | ALAS2 | ENSPPYP00000021874 | ENSPPYP00000022824 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.726 |
ALAD | CPOX | ENSPPYP00000021874 | ENSPPYP00000015217 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Coproporphyrinogen oxidase. | 0.819 |
ALAD | FASN | ENSPPYP00000021874 | ENSPPYP00000009843 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | FASN isoform 1. | 0.865 |
ALAD | FECH | ENSPPYP00000021874 | ENSPPYP00000010312 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.730 |
ALAD | HMBS | ENSPPYP00000021874 | ENSPPYP00000004531 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | HMBS isoform 3. | 0.999 |
ALAD | OAT | ENSPPYP00000021874 | ENSPPYP00000024470 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | OAT isoform 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.919 |
ALAD | UROD | ENSPPYP00000021874 | ENSPPYP00000001644 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.875 |
ALAD | UROS | ENSPPYP00000021874 | ENSPPYP00000003214 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Uroporphyrinogen III synthase. | 0.992 |
ALAS1 | ALAD | ENSPPYP00000015461 | ENSPPYP00000021874 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.977 |
ALAS1 | ALAS2 | ENSPPYP00000015461 | ENSPPYP00000022824 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.533 |
ALAS1 | CPOX | ENSPPYP00000015461 | ENSPPYP00000015217 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Coproporphyrinogen oxidase. | 0.531 |
ALAS1 | FECH | ENSPPYP00000015461 | ENSPPYP00000010312 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. | 0.697 |
ALAS1 | HMBS | ENSPPYP00000015461 | ENSPPYP00000004531 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | HMBS isoform 3. | 0.689 |
ALAS1 | UROD | ENSPPYP00000015461 | ENSPPYP00000001644 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.575 |
ALAS1 | UROS | ENSPPYP00000015461 | ENSPPYP00000003214 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen III synthase. | 0.497 |
ALAS2 | ALAD | ENSPPYP00000022824 | ENSPPYP00000021874 | 5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.726 |