node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5PO | DDX3X | ENSPPYP00000012709 | ENSPPYP00000022671 | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | 0.640 |
ATP5PO | EFTUD2 | ENSPPYP00000012709 | ENSPPYP00000009352 | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.740 |
ATP5PO | KDM6A | ENSPPYP00000012709 | ENSPPYP00000022687 | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | UTY isoform 5. | 0.889 |
ATP5PO | RPL23A | ENSPPYP00000012709 | ENSPPYP00000009116 | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | RPL23A isoform 1; Belongs to the universal ribosomal protein uL23 family. | 0.626 |
CTPS2 | DDX3X | ENSPPYP00000022544 | ENSPPYP00000022671 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | 0.663 |
CTPS2 | EFTUD2 | ENSPPYP00000022544 | ENSPPYP00000009352 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.410 |
CTPS2 | EIF2S3 | ENSPPYP00000022544 | ENSPPYP00000022595 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...] | 0.799 |
CTPS2 | KDM6A | ENSPPYP00000022544 | ENSPPYP00000022687 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | UTY isoform 5. | 0.794 |
CTPS2 | RPL23A | ENSPPYP00000022544 | ENSPPYP00000009116 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | RPL23A isoform 1; Belongs to the universal ribosomal protein uL23 family. | 0.474 |
DDX3X | ATP5PO | ENSPPYP00000022671 | ENSPPYP00000012709 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | 0.640 |
DDX3X | CTPS2 | ENSPPYP00000022671 | ENSPPYP00000022544 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.663 |
DDX3X | EFTUD2 | ENSPPYP00000022671 | ENSPPYP00000009352 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | 0.692 |
DDX3X | EIF2S3 | ENSPPYP00000022671 | ENSPPYP00000022595 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...] | 0.648 |
DDX3X | EIF4E | ENSPPYP00000022671 | ENSPPYP00000016686 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | EIF4E isoform 1; Belongs to the eukaryotic initiation factor 4E family. | 0.688 |
DDX3X | KDM6A | ENSPPYP00000022671 | ENSPPYP00000022687 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | UTY isoform 5. | 0.640 |
DDX3X | PES1 | ENSPPYP00000022671 | ENSPPYP00000013069 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.626 |
DDX3X | PRPF6 | ENSPPYP00000022671 | ENSPPYP00000012574 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | Pre-mRNA-processing factor 6; Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. | 0.715 |
DDX3X | RPL23A | ENSPPYP00000022671 | ENSPPYP00000009116 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | RPL23A isoform 1; Belongs to the universal ribosomal protein uL23 family. | 0.633 |
DDX3X | TBK1 | ENSPPYP00000022671 | ENSPPYP00000005386 | ATP-dependent RNA helicase DDX3Y; Probable ATP-dependent RNA helicase. May play a role in spermatogenesis (By similarity); Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. | TANK binding kinase 1. | 0.964 |
EFTUD2 | ATP5PO | ENSPPYP00000009352 | ENSPPYP00000012709 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). | ATP synthase subunit O, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] | 0.740 |