Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MICU1 | MICU2 | ENSPPYP00000002731 | ENSPPYP00000024750 | Mitochondrial calcium uptake 1. | MICU2 isoform 2. | 0.999 |
MICU1 | NDUFA8 | ENSPPYP00000002731 | ENSPPYP00000022282 | Mitochondrial calcium uptake 1. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.758 |
MICU1 | NDUFB10 | ENSPPYP00000002731 | ENSPPYP00000007895 | Mitochondrial calcium uptake 1. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.760 |
MICU1 | PARL | ENSPPYP00000002731 | ENSPPYP00000024436 | Mitochondrial calcium uptake 1. | Presenilins-associated rhomboid-like protein, mitochondrial; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity). Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity). | 0.752 |
MICU1 | PHB2 | ENSPPYP00000002731 | ENSPPYP00000004803 | Mitochondrial calcium uptake 1. | Prohibitin-2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity). In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1- [...] | 0.894 |
MICU1 | SLC25A13 | ENSPPYP00000002731 | ENSPPYP00000019950 | Mitochondrial calcium uptake 1. | SLC25A13 isoform 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.413 |
MICU1 | STOML2 | ENSPPYP00000002731 | ENSPPYP00000021405 | Mitochondrial calcium uptake 1. | STOML2 isoform 3. | 0.419 |
MICU1 | TIMM21 | ENSPPYP00000002731 | ENSPPYP00000010367 | Mitochondrial calcium uptake 1. | Mitochondrial import inner membrane translocase subunit Tim21; Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. | 0.767 |
MICU1 | TIMM50 | ENSPPYP00000002731 | ENSPPYP00000011161 | Mitochondrial calcium uptake 1. | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. | 0.749 |
MICU2 | MICU1 | ENSPPYP00000024750 | ENSPPYP00000002731 | MICU2 isoform 2. | Mitochondrial calcium uptake 1. | 0.999 |
MICU2 | NDUFA8 | ENSPPYP00000024750 | ENSPPYP00000022282 | MICU2 isoform 2. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.757 |
MICU2 | NDUFB10 | ENSPPYP00000024750 | ENSPPYP00000007895 | MICU2 isoform 2. | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.760 |
MICU2 | PARL | ENSPPYP00000024750 | ENSPPYP00000024436 | MICU2 isoform 2. | Presenilins-associated rhomboid-like protein, mitochondrial; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity). Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity). | 0.741 |
MICU2 | PHB2 | ENSPPYP00000024750 | ENSPPYP00000004803 | MICU2 isoform 2. | Prohibitin-2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity). In mitochondria, regulates cytochrome-c oxidase assembly (COX) and mitochondrial respiration. Binding to sphingoid 1- [...] | 0.886 |
MICU2 | SLC25A13 | ENSPPYP00000024750 | ENSPPYP00000019950 | MICU2 isoform 2. | SLC25A13 isoform 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.551 |
MICU2 | STOML2 | ENSPPYP00000024750 | ENSPPYP00000021405 | MICU2 isoform 2. | STOML2 isoform 3. | 0.419 |
MICU2 | TIMM21 | ENSPPYP00000024750 | ENSPPYP00000010367 | MICU2 isoform 2. | Mitochondrial import inner membrane translocase subunit Tim21; Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. | 0.767 |
MICU2 | TIMM50 | ENSPPYP00000024750 | ENSPPYP00000011161 | MICU2 isoform 2. | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. | 0.748 |
NDUFA8 | MICU1 | ENSPPYP00000022282 | ENSPPYP00000002731 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Mitochondrial calcium uptake 1. | 0.758 |
NDUFA8 | MICU2 | ENSPPYP00000022282 | ENSPPYP00000024750 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | MICU2 isoform 2. | 0.757 |
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