STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FNDC8Fibronectin type III domain containing 8. (324 aa)    
Predicted Functional Partners:
SCP2D1
SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.
   
  
 0.670
MGAT4D
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis; Belongs to the glycosyltransferase 54 family.
   
  
 0.609
SYNGR4
Synaptogyrin-4; Synaptogyrin 4.
   
  
 0.607
GLB1L
Beta-galactosidase-1-like protein; Probable glycosyl hydrolase.
   
  
 0.594
FSCN3
Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family.
   
  
 0.542
TEX13A
Testis-expressed protein 13A; Testis expressed 13A; Belongs to the TEX13 family.
   
  
 0.530
FAM221B
Protein FAM221B; Family with sequence similarity 221 member B.
   
  
 0.503
SLC36A3
Proton-coupled amino acid transporter 3; Solute carrier family 36 member 3.
   
  
 0.486
TMEM202
Transmembrane protein 202.
      
 0.480
HMGB4
High mobility group box 4; Belongs to the HMGB family.
   
  
 0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.