node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTBD2 | FAM214A | ENSP00000255608 | ENSP00000443598 | BTB/POZ domain-containing protein 2; BTB domain containing 2. | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | 0.419 |
BTBD2 | LMBRD2 | ENSP00000255608 | ENSP00000296603 | BTB/POZ domain-containing protein 2; BTB domain containing 2. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | 0.466 |
FAM214A | BTBD2 | ENSP00000443598 | ENSP00000255608 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | BTB/POZ domain-containing protein 2; BTB domain containing 2. | 0.419 |
FAM214A | KBTBD4 | ENSP00000443598 | ENSP00000436713 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | Kelch repeat and BTB domain containing 4. | 0.416 |
FAM214A | LMBRD2 | ENSP00000443598 | ENSP00000296603 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | 0.573 |
FAM214A | MBLAC1 | ENSP00000443598 | ENSP00000381150 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | Metallo-beta-lactamase domain containing 1. | 0.488 |
FAM214A | ONECUT1 | ENSP00000443598 | ENSP00000302630 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | Hepatocyte nuclear factor 6; Transcriptional activator. Binds the consensus sequence 5'- DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription; Belongs to the CUT homeobox family. | 0.476 |
FAM214A | PIGO | ENSP00000443598 | ENSP00000367880 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI- anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. | 0.426 |
FAM214A | RSL24D1 | ENSP00000443598 | ENSP00000260443 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity); Belongs to the eukaryotic ribosomal protein eL24 family. | 0.544 |
FAM214A | WDR72 | ENSP00000443598 | ENSP00000379619 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | WD repeat-containing protein 72; Plays a major role in formation of tooth enamel. Specifically required during the maturation phase of amelogenesis for normal formation of the enamel matrix and clearance of enamel proteins. May be involved in localization of the calcium transporter SLC24A4 to the ameloblast cell membrane. | 0.459 |
FAM214A | ZC3H6 | ENSP00000443598 | ENSP00000386764 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | Zinc finger CCCH-type containing 6. | 0.451 |
FAM214A | ZFAND2B | ENSP00000443598 | ENSP00000289528 | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | AN1-type zinc finger protein 2B; Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum. It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum. It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed. May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism tha [...] | 0.481 |
KBTBD4 | FAM214A | ENSP00000436713 | ENSP00000443598 | Kelch repeat and BTB domain containing 4. | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | 0.416 |
KBTBD4 | MBLAC1 | ENSP00000436713 | ENSP00000381150 | Kelch repeat and BTB domain containing 4. | Metallo-beta-lactamase domain containing 1. | 0.460 |
KBTBD4 | ZC3H6 | ENSP00000436713 | ENSP00000386764 | Kelch repeat and BTB domain containing 4. | Zinc finger CCCH-type containing 6. | 0.424 |
LMBRD2 | BTBD2 | ENSP00000296603 | ENSP00000255608 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | BTB/POZ domain-containing protein 2; BTB domain containing 2. | 0.466 |
LMBRD2 | FAM214A | ENSP00000296603 | ENSP00000443598 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | 0.573 |
LMBRD2 | PIGO | ENSP00000296603 | ENSP00000367880 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI- anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. | 0.497 |
LMBRD2 | RSL24D1 | ENSP00000296603 | ENSP00000260443 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity); Belongs to the eukaryotic ribosomal protein eL24 family. | 0.450 |
MBLAC1 | FAM214A | ENSP00000381150 | ENSP00000443598 | Metallo-beta-lactamase domain containing 1. | Protein FAM214A; Family with sequence similarity 214 member A; Belongs to the FAM214 family. | 0.488 |