node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BEX5 | MAGEA8 | ENSP00000446054 | ENSP00000438293 | Protein BEX5; Brain expressed X-linked 5; Belongs to the BEX family. | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.627 |
CTAG1B | FMR1NB | ENSP00000332602 | ENSP00000359498 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | 0.419 |
CTAG1B | MAGEA8 | ENSP00000332602 | ENSP00000438293 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.433 |
FMR1NB | CTAG1B | ENSP00000359498 | ENSP00000332602 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | 0.419 |
FMR1NB | HSFX4 | ENSP00000359498 | ENSP00000489814 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | Heat shock transcription factor family, X-linked member 4. | 0.542 |
FMR1NB | MAGEA8 | ENSP00000359498 | ENSP00000438293 | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.431 |
GCA | MAGEA8 | ENSP00000394842 | ENSP00000438293 | Grancalcin; Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions. | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.692 |
HSFX4 | FMR1NB | ENSP00000489814 | ENSP00000359498 | Heat shock transcription factor family, X-linked member 4. | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | 0.542 |
HSFX4 | MAGEA8 | ENSP00000489814 | ENSP00000438293 | Heat shock transcription factor family, X-linked member 4. | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.512 |
MAGEA8 | BEX5 | ENSP00000438293 | ENSP00000446054 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Protein BEX5; Brain expressed X-linked 5; Belongs to the BEX family. | 0.627 |
MAGEA8 | CTAG1B | ENSP00000438293 | ENSP00000332602 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | 0.433 |
MAGEA8 | FMR1NB | ENSP00000438293 | ENSP00000359498 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. | 0.431 |
MAGEA8 | GCA | ENSP00000438293 | ENSP00000394842 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Grancalcin; Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions. | 0.692 |
MAGEA8 | HSFX4 | ENSP00000438293 | ENSP00000489814 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Heat shock transcription factor family, X-linked member 4. | 0.512 |
MAGEA8 | NSMCE1 | ENSP00000438293 | ENSP00000355077 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Non-structural maintenance of chromosomes element 1 homolog; RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. Involved in maintenance of genome integrity, DNA damage response and DNA repair. NSMCE3/MAGEG1 and NSMCE [...] | 0.500 |
MAGEA8 | NSMCE2 | ENSP00000438293 | ENSP00000287437 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | E3 SUMO-protein ligase NSE2; E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. Is not be required for the stability of the complex. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin com [...] | 0.475 |
MAGEA8 | SMC5 | ENSP00000438293 | ENSP00000354957 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies ( [...] | 0.494 |
MAGEA8 | SMC6 | ENSP00000438293 | ENSP00000404092 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Req [...] | 0.492 |
MAGEA8 | TDRD7 | ENSP00000438293 | ENSP00000347444 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Tudor domain-containing protein 7; Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis; Belongs to the TDRD7 family. | 0.457 |
NSMCE1 | MAGEA8 | ENSP00000355077 | ENSP00000438293 | Non-structural maintenance of chromosomes element 1 homolog; RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex. Involved in maintenance of genome integrity, DNA damage response and DNA repair. NSMCE3/MAGEG1 and NSMCE [...] | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.500 |