node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN2 | ATXN2L | ENSP00000446576 | ENSP00000378917 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | 0.953 |
ATXN2 | C6orf52 | ENSP00000446576 | ENSP00000259983 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | Putative uncharacterized protein C6orf52; Chromosome 6 open reading frame 52. | 0.582 |
ATXN2 | DDX6 | ENSP00000446576 | ENSP00000478754 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.993 |
ATXN2 | LSM12 | ENSP00000446576 | ENSP00000466718 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | LSM12 homolog. | 0.985 |
ATXN2 | NUFIP2 | ENSP00000446576 | ENSP00000225388 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | Nuclear fragile X mental retardation-interacting protein 2; Binds RNA. | 0.816 |
ATXN2 | TRNAU1AP | ENSP00000446576 | ENSP00000362936 | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity); Belongs to the RRM TRSPAP family. | 0.643 |
ATXN2L | ATXN2 | ENSP00000378917 | ENSP00000446576 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | 0.953 |
ATXN2L | C6orf52 | ENSP00000378917 | ENSP00000259983 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | Putative uncharacterized protein C6orf52; Chromosome 6 open reading frame 52. | 0.582 |
ATXN2L | DDX6 | ENSP00000378917 | ENSP00000478754 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | 0.952 |
ATXN2L | LSM12 | ENSP00000378917 | ENSP00000466718 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | LSM12 homolog. | 0.986 |
ATXN2L | MCRIP2 | ENSP00000378917 | ENSP00000305138 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | MAPK regulated corepressor interacting protein 2; Belongs to the MCRIP family. | 0.617 |
ATXN2L | NUFIP2 | ENSP00000378917 | ENSP00000225388 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | Nuclear fragile X mental retardation-interacting protein 2; Binds RNA. | 0.906 |
ATXN2L | TRNAU1AP | ENSP00000378917 | ENSP00000362936 | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis (By similarity); Belongs to the RRM TRSPAP family. | 0.582 |
C6orf52 | ATXN2 | ENSP00000259983 | ENSP00000446576 | Putative uncharacterized protein C6orf52; Chromosome 6 open reading frame 52. | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | 0.582 |
C6orf52 | ATXN2L | ENSP00000259983 | ENSP00000378917 | Putative uncharacterized protein C6orf52; Chromosome 6 open reading frame 52. | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | 0.582 |
C6orf52 | LSM12 | ENSP00000259983 | ENSP00000466718 | Putative uncharacterized protein C6orf52; Chromosome 6 open reading frame 52. | LSM12 homolog. | 0.752 |
DDX6 | ATXN2 | ENSP00000478754 | ENSP00000446576 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Ataxin-2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane. | 0.993 |
DDX6 | ATXN2L | ENSP00000478754 | ENSP00000378917 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | Ataxin-2-like protein; Involved in the regulation of stress granule and P-body formation. | 0.952 |
DDX6 | LSM12 | ENSP00000478754 | ENSP00000466718 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | LSM12 homolog. | 0.945 |
DDX6 | LSM2 | ENSP00000478754 | ENSP00000364813 | Probable ATP-dependent RNA helicase DDX6; In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. | U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.861 |