STRINGSTRING
NSA2 protein (human) - STRING interaction network
NSA2 ribosome biogenesis homolog (S. cerevisiae) in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
NSA2NSA2 ribosome biogenesis homolog (S. cerevisiae); Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity) (260 aa)    
Predicted Functional Partners:
GTPBP4
GTP binding protein 4; Involved in the biogenesis of the 60S ribosomal subunit (634 aa)
     
 
  0.999
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein (293 aa)
     
 
  0.999
GNL2
Guanine nucleotide binding protein-like 2 (nucleolar); GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (731 aa)
     
 
  0.999
RSL24D1
Ribosomal L24 domain containing 1; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity) (163 aa)
     
 
  0.998
RPF2
Ribosome production factor 2 homolog (S. cerevisiae) (306 aa)
     
 
  0.998
MRTO4
mRNA turnover 4 homolog (S. cerevisiae); Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes (239 aa)
     
 
  0.997
NLE1
Notchless homolog 1 (Drosophila); Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity) (485 aa)
     
 
  0.996
RPS3A
Ribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (264 aa)
     
 
  0.995
RPS6
Ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (249 aa)
     
 
  0.995
RPS15A
Ribosomal protein S15a (130 aa)
     
 
  0.995
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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