STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF80Zinc finger protein 80; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (273 aa)    
Predicted Functional Partners:
PRB3
Basic salivary proline-rich protein 3; Acts as a receptor for the Gram-negative bacterium F.nucleatum.
    
 
 0.680
GPR15
G-protein coupled receptor 15; Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.603
FAM187B
Protein FAM187B; Family with sequence similarity 187 member B.
   
  
 0.578
OR7G3
Olfactory receptor 7G3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.560
SLC22A24
Steroid transmembrane transporter SLC22A24; Steroid transmembrane transporter that functions in the reabsorption of conjugated steroids in the kidney and is involved in steroid homeostasis. [Isoform 3]: Lack of transporter activity.
    
 
 0.497
CBY2
Chibby family member 2.
    
 
 0.495
ABCA10
ATP-binding cassette sub-family A member 10; Probable transporter which may play a role in macrophage lipid homeostasis.
    
 
 0.446
CCHCR1
Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.
    
 
 0.427
KRT83
Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family.
   
 
 0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.