node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC102A | CCDC102B | ENSP00000258214 | ENSP00000353377 | Coiled-coil domain containing 102A. | Coiled-coil domain containing 102B. | 0.518 |
CCDC102B | CCDC102A | ENSP00000353377 | ENSP00000258214 | Coiled-coil domain containing 102B. | Coiled-coil domain containing 102A. | 0.518 |
CCDC102B | CCDC15 | ENSP00000353377 | ENSP00000341684 | Coiled-coil domain containing 102B. | Coiled-coil domain containing 15. | 0.486 |
CCDC102B | CEP44 | ENSP00000353377 | ENSP00000389427 | Coiled-coil domain containing 102B. | Centrosomal protein 44. | 0.504 |
CCDC102B | DOK6 | ENSP00000353377 | ENSP00000372160 | Coiled-coil domain containing 102B. | Docking protein 6; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. | 0.552 |
CCDC102B | ELOVL2 | ENSP00000353377 | ENSP00000346693 | Coiled-coil domain containing 102B. | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the productio [...] | 0.570 |
CCDC102B | ELOVL5 | ENSP00000353377 | ENSP00000359956 | Coiled-coil domain containing 102B. | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | 0.459 |
CCDC102B | L3MBTL4 | ENSP00000353377 | ENSP00000382976 | Coiled-coil domain containing 102B. | Lethal(3)malignant brain tumor-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). | 0.470 |
CCDC102B | PDE4C | ENSP00000353377 | ENSP00000469696 | Coiled-coil domain containing 102B. | Phosphodiesterase 4C. | 0.480 |
CCDC102B | PDE4C-2 | ENSP00000353377 | ENSP00000347689 | Coiled-coil domain containing 102B. | cAMP-specific 3',5'-cyclic phosphodiesterase 4C; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. | 0.479 |
CCDC102B | RTTN | ENSP00000353377 | ENSP00000491507 | Coiled-coil domain containing 102B. | Rotatin; Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2. | 0.608 |
CCDC15 | CCDC102B | ENSP00000341684 | ENSP00000353377 | Coiled-coil domain containing 15. | Coiled-coil domain containing 102B. | 0.486 |
CEP44 | CCDC102B | ENSP00000389427 | ENSP00000353377 | Centrosomal protein 44. | Coiled-coil domain containing 102B. | 0.504 |
CEP44 | RTTN | ENSP00000389427 | ENSP00000491507 | Centrosomal protein 44. | Rotatin; Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2. | 0.513 |
DOK6 | CCDC102B | ENSP00000372160 | ENSP00000353377 | Docking protein 6; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. | Coiled-coil domain containing 102B. | 0.552 |
DOK6 | RTTN | ENSP00000372160 | ENSP00000491507 | Docking protein 6; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. | Rotatin; Involved in the genetic cascade that governs left-right specification. Plays a role in the maintenance of a normal ciliary structure. Required for correct asymmetric expression of NODAL, LEFTY and PITX2. | 0.520 |
ELOVL2 | CCDC102B | ENSP00000346693 | ENSP00000353377 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the productio [...] | Coiled-coil domain containing 102B. | 0.570 |
ELOVL2 | PDE4C | ENSP00000346693 | ENSP00000469696 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the productio [...] | Phosphodiesterase 4C. | 0.581 |
ELOVL2 | PDE4C-2 | ENSP00000346693 | ENSP00000347689 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the productio [...] | cAMP-specific 3',5'-cyclic phosphodiesterase 4C; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. | 0.580 |
ELOVL5 | CCDC102B | ENSP00000359956 | ENSP00000353377 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] | Coiled-coil domain containing 102B. | 0.459 |