node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GIN1 | HARBI1 | ENSP00000381970 | ENSP00000317743 | Gypsy retrotransposon integrase 1. | Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. | 0.603 |
GIN1 | PGBD1 | ENSP00000381970 | ENSP00000259883 | Gypsy retrotransposon integrase 1. | piggyBac transposable element derived 1. | 0.513 |
GIN1 | PGBD5 | ENSP00000381970 | ENSP00000375733 | Gypsy retrotransposon integrase 1. | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | 0.674 |
GIN1 | RAG1 | ENSP00000381970 | ENSP00000299440 | Gypsy retrotransposon integrase 1. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.444 |
GIN1 | THAP9 | ENSP00000381970 | ENSP00000305533 | Gypsy retrotransposon integrase 1. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.590 |
HARBI1 | GIN1 | ENSP00000317743 | ENSP00000381970 | Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. | Gypsy retrotransposon integrase 1. | 0.603 |
HARBI1 | PGBD5 | ENSP00000317743 | ENSP00000375733 | Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | 0.663 |
HARBI1 | THAP9 | ENSP00000317743 | ENSP00000305533 | Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.592 |
PGBD1 | GIN1 | ENSP00000259883 | ENSP00000381970 | piggyBac transposable element derived 1. | Gypsy retrotransposon integrase 1. | 0.513 |
PGBD1 | PGBD5 | ENSP00000259883 | ENSP00000375733 | piggyBac transposable element derived 1. | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | 0.563 |
PGBD1 | THAP9 | ENSP00000259883 | ENSP00000305533 | piggyBac transposable element derived 1. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.537 |
PGBD5 | GIN1 | ENSP00000375733 | ENSP00000381970 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Gypsy retrotransposon integrase 1. | 0.674 |
PGBD5 | HARBI1 | ENSP00000375733 | ENSP00000317743 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. | 0.663 |
PGBD5 | PGBD1 | ENSP00000375733 | ENSP00000259883 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | piggyBac transposable element derived 1. | 0.563 |
PGBD5 | PIP5K1A | ENSP00000375733 | ENSP00000357883 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5- trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4- phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as actin cytoskeleton organ [...] | 0.562 |
PGBD5 | RABGGTB | ENSP00000375733 | ENSP00000317473 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A; Belongs to the protein prenyltransferase subunit beta family. | 0.601 |
PGBD5 | RAG1 | ENSP00000375733 | ENSP00000299440 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] | 0.542 |
PGBD5 | SETMAR | ENSP00000375733 | ENSP00000373354 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Histone-lysine N-methyltransferase SETMAR; Protein derived from the fusion of a methylase with the transposase of an Hsmar1 transposon that plays a role in DNA double- strand break repair, stalled replication fork restart and DNA integration. DNA-binding protein, it is indirectly recruited to sites of DNA damage through protein-protein interactions. Has also kept a sequence-specific DNA-binding activity recognizing the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element and displays a DNA nicking and end joining activity. In parallel, has a histone methyltransf [...] | 0.586 |
PGBD5 | THAP9 | ENSP00000375733 | ENSP00000305533 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | DNA transposase THAP9; Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transposition. | 0.802 |
PGBD5 | TMEM145 | ENSP00000375733 | ENSP00000301204 | PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene. | Transmembrane protein 145. | 0.627 |