node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDKL5 | NHS | ENSP00000369325 | ENSP00000369400 | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | 0.730 |
CDKL5 | RAI2 | ENSP00000369325 | ENSP00000444210 | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | Retinoic acid induced 2. | 0.800 |
CDKL5 | SCML2 | ENSP00000369325 | ENSP00000251900 | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | Sex comb on midleg-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). | 0.694 |
DEPDC1B | LMBRD2 | ENSP00000265036 | ENSP00000296603 | DEP domain containing 1B. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | 0.511 |
DEPDC1B | NHS | ENSP00000265036 | ENSP00000369400 | DEP domain containing 1B. | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | 0.410 |
DEPDC1B | RAI2 | ENSP00000265036 | ENSP00000444210 | DEP domain containing 1B. | Retinoic acid induced 2. | 0.448 |
FAU | RAI2 | ENSP00000431822 | ENSP00000444210 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Retinoic acid induced 2. | 0.806 |
GCNT2 | NHS | ENSP00000419411 | ENSP00000369400 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells; Belongs to the glycosyltransferase 14 family. | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | 0.768 |
GCNT2 | RAI2 | ENSP00000419411 | ENSP00000444210 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells; Belongs to the glycosyltransferase 14 family. | Retinoic acid induced 2. | 0.553 |
LMBRD2 | DEPDC1B | ENSP00000296603 | ENSP00000265036 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | DEP domain containing 1B. | 0.511 |
LMBRD2 | RAI2 | ENSP00000296603 | ENSP00000444210 | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1 (Probable); Belongs to the LIMR family. | Retinoic acid induced 2. | 0.478 |
NHS | CDKL5 | ENSP00000369400 | ENSP00000369325 | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | 0.730 |
NHS | DEPDC1B | ENSP00000369400 | ENSP00000265036 | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | DEP domain containing 1B. | 0.410 |
NHS | GCNT2 | ENSP00000369400 | ENSP00000419411 | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells; Belongs to the glycosyltransferase 14 family. | 0.768 |
NHS | RAI2 | ENSP00000369400 | ENSP00000444210 | Nance-Horan syndrome protein; May function in cell morphology by maintaining the integrity of the circumferential actin ring and controlling lamellipod formation. Involved in the regulation eye, tooth, brain and craniofacial development; Belongs to the NHS family. | Retinoic acid induced 2. | 0.958 |
PALM2AKAP2 | RAI2 | ENSP00000363654 | ENSP00000444210 | A-kinase anchor protein 2; Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). | Retinoic acid induced 2. | 0.422 |
RAI2 | CDKL5 | ENSP00000444210 | ENSP00000369325 | Retinoic acid induced 2. | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | 0.800 |
RAI2 | DEPDC1B | ENSP00000444210 | ENSP00000265036 | Retinoic acid induced 2. | DEP domain containing 1B. | 0.448 |
RAI2 | FAU | ENSP00000444210 | ENSP00000431822 | Retinoic acid induced 2. | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 0.806 |
RAI2 | GCNT2 | ENSP00000444210 | ENSP00000419411 | Retinoic acid induced 2. | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase; Branching enzyme that converts linear into branched poly-N- acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells; Belongs to the glycosyltransferase 14 family. | 0.553 |