node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKEF1 | ZNF226 | ENSP00000367644 | ENSP00000465121 | Ankyrin repeat and EF-hand domain containing 1. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.411 |
CCDC51 | TMA7 | ENSP00000379047 | ENSP00000397843 | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | Translation machinery associated 7 homolog. | 0.419 |
CCDC51 | ZNF226 | ENSP00000379047 | ENSP00000465121 | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.480 |
KRBOX4 | TRIM28 | ENSP00000345797 | ENSP00000253024 | KRAB box domain containing 4. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.654 |
KRBOX4 | ZNF226 | ENSP00000345797 | ENSP00000465121 | KRAB box domain containing 4. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.437 |
LRRC46 | ZNF226 | ENSP00000269025 | ENSP00000465121 | Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.417 |
MRPL58 | ZNF226 | ENSP00000301585 | ENSP00000465121 | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.411 |
TMA7 | CCDC51 | ENSP00000397843 | ENSP00000379047 | Translation machinery associated 7 homolog. | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | 0.419 |
TMA7 | ZNF226 | ENSP00000397843 | ENSP00000465121 | Translation machinery associated 7 homolog. | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.419 |
TRIM28 | KRBOX4 | ENSP00000253024 | ENSP00000345797 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | KRAB box domain containing 4. | 0.654 |
TRIM28 | ZNF226 | ENSP00000253024 | ENSP00000465121 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 226; May be involved in transcriptional regulation. | 0.585 |
ZNF226 | ANKEF1 | ENSP00000465121 | ENSP00000367644 | Zinc finger protein 226; May be involved in transcriptional regulation. | Ankyrin repeat and EF-hand domain containing 1. | 0.411 |
ZNF226 | CCDC51 | ENSP00000465121 | ENSP00000379047 | Zinc finger protein 226; May be involved in transcriptional regulation. | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | 0.480 |
ZNF226 | KRBOX4 | ENSP00000465121 | ENSP00000345797 | Zinc finger protein 226; May be involved in transcriptional regulation. | KRAB box domain containing 4. | 0.437 |
ZNF226 | LRRC46 | ENSP00000465121 | ENSP00000269025 | Zinc finger protein 226; May be involved in transcriptional regulation. | Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46. | 0.417 |
ZNF226 | MRPL58 | ENSP00000465121 | ENSP00000301585 | Zinc finger protein 226; May be involved in transcriptional regulation. | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | 0.411 |
ZNF226 | TMA7 | ENSP00000465121 | ENSP00000397843 | Zinc finger protein 226; May be involved in transcriptional regulation. | Translation machinery associated 7 homolog. | 0.419 |
ZNF226 | TRIM28 | ENSP00000465121 | ENSP00000253024 | Zinc finger protein 226; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.585 |