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ZNF323 protein (human) - STRING interaction network
"ZNF323" - Zinc finger protein 323 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF323Zinc finger protein 323; May function as a transcription factor. May be involved in the development of multiple embryonic organs (406 aa)    
Predicted Functional Partners:
POTEE
POTE ankyrin domain family member E (1075 aa)
     
 
  0.568
POTEI
POTE ankyrin domain family, member I (1075 aa)
     
 
  0.568
POTEJ
POTE ankyrin domain family, member J (1038 aa)
     
 
  0.568
POTEF
POTE ankyrin domain family, member F (1075 aa)
     
 
  0.568
RIPK4
Receptor-interacting serine-threonine kinase 4 (784 aa)
     
 
  0.509
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on ’Ser-473’ of AKT1, ’Ser-660’ of PRKCB isoform beta-II and ’Ser-657’ of PRKCA. Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of ’Ser- 473’ of Akt triggers apoptosis an [...] (1323 aa)
     
 
  0.481
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on ’Ser-473’ of AKT2 and AKT3, ’Ser-660’ of PRKCB and ’Ser-657’ of PRKCA (PubMed-15808505, PubMed-17386267, PubMed-18162466). Isoform 2 seems to have a major role in regulating Akt signaling in hippocampal neurons (By similarity). Akt regulates the balance between cell survival and apoptosis through a cascade that primarily [...] (1717 aa)
     
 
  0.481
LRRK2
Leucine-rich repeat kinase 2; Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (C [...] (2527 aa)
     
 
  0.415
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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