node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COMMD7 | NOL4L | ENSP00000278980 | ENSP00000483523 | COMM domain-containing protein 7; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Associates with the NF-kappa-B complex and suppresses its transcriptional activity. | Nucleolar protein 4 like. | 0.462 |
CTBP1 | CTBP2 | ENSP00000290921 | ENSP00000311825 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.999 |
CTBP1 | NOL4 | ENSP00000290921 | ENSP00000261592 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Nucleolar protein 4. | 0.685 |
CTBP1 | NOL4L | ENSP00000290921 | ENSP00000483523 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Nucleolar protein 4 like. | 0.821 |
CTBP1 | RUNX1 | ENSP00000290921 | ENSP00000300305 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Runt-related transcription factor 1; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T [...] | 0.973 |
CTBP2 | CTBP1 | ENSP00000311825 | ENSP00000290921 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.999 |
CTBP2 | NOL4 | ENSP00000311825 | ENSP00000261592 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Nucleolar protein 4. | 0.406 |
CTBP2 | NOL4L | ENSP00000311825 | ENSP00000483523 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Nucleolar protein 4 like. | 0.483 |
CTBP2 | RUNX1 | ENSP00000311825 | ENSP00000300305 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Runt-related transcription factor 1; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T [...] | 0.942 |
FAM227B | NOL4L | ENSP00000299338 | ENSP00000483523 | Protein FAM227B; Family with sequence similarity 227 member B. | Nucleolar protein 4 like. | 0.498 |
KIF3B | NOL4L | ENSP00000364864 | ENSP00000483523 | Kinesin-like protein KIF3B, N-terminally processed; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity). | Nucleolar protein 4 like. | 0.476 |
NOL4 | CTBP1 | ENSP00000261592 | ENSP00000290921 | Nucleolar protein 4. | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.685 |
NOL4 | CTBP2 | ENSP00000261592 | ENSP00000311825 | Nucleolar protein 4. | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.406 |
NOL4 | NOL4L | ENSP00000261592 | ENSP00000483523 | Nucleolar protein 4. | Nucleolar protein 4 like. | 0.618 |
NOL4 | SKA3 | ENSP00000261592 | ENSP00000319417 | Nucleolar protein 4. | Spindle and kinetochore-associated protein 3; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule- stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the [...] | 0.459 |
NOL4 | TEX9 | ENSP00000261592 | ENSP00000342169 | Nucleolar protein 4. | Testis-expressed protein 9; Testis expressed 9. | 0.669 |
NOL4L | COMMD7 | ENSP00000483523 | ENSP00000278980 | Nucleolar protein 4 like. | COMM domain-containing protein 7; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Associates with the NF-kappa-B complex and suppresses its transcriptional activity. | 0.462 |
NOL4L | CTBP1 | ENSP00000483523 | ENSP00000290921 | Nucleolar protein 4 like. | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.821 |
NOL4L | CTBP2 | ENSP00000483523 | ENSP00000311825 | Nucleolar protein 4 like. | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.483 |
NOL4L | FAM227B | ENSP00000483523 | ENSP00000299338 | Nucleolar protein 4 like. | Protein FAM227B; Family with sequence similarity 227 member B. | 0.498 |