node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD1 | C3orf18 | ENSP00000326491 | ENSP00000349732 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | 0.522 |
ABHD1 | FAM3A | ENSP00000326491 | ENSP00000320521 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | 0.482 |
ABHD1 | HEATR1 | ENSP00000326491 | ENSP00000355541 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | HEAT repeat-containing protein 1, N-terminally processed; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family. | 0.454 |
ABHD1 | UNC45A | ENSP00000326491 | ENSP00000407487 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | Protein unc-45 homolog A; Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity). | 0.456 |
ABHD1 | UNC45B | ENSP00000326491 | ENSP00000268876 | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | Protein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. | 0.434 |
C3orf18 | ABHD1 | ENSP00000349732 | ENSP00000326491 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | 0.522 |
C3orf18 | FAM3A | ENSP00000349732 | ENSP00000320521 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | 0.498 |
C3orf18 | HEATR1 | ENSP00000349732 | ENSP00000355541 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | HEAT repeat-containing protein 1, N-terminally processed; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family. | 0.490 |
C3orf18 | UNC45A | ENSP00000349732 | ENSP00000407487 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Protein unc-45 homolog A; Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity). | 0.461 |
C3orf18 | UNC45B | ENSP00000349732 | ENSP00000268876 | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | Protein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. | 0.443 |
COQ4 | FAM3A | ENSP00000300452 | ENSP00000320521 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | 0.442 |
FAM3A | ABHD1 | ENSP00000320521 | ENSP00000326491 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Protein ABHD1; Abhydrolase domain containing 1; Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. | 0.482 |
FAM3A | C3orf18 | ENSP00000320521 | ENSP00000349732 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Uncharacterized protein C3orf18; Chromosome 3 open reading frame 18. | 0.498 |
FAM3A | COQ4 | ENSP00000320521 | ENSP00000300452 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. | 0.442 |
FAM3A | FAM50A | ENSP00000320521 | ENSP00000377225 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Protein FAM50A; May be a DNA-binding protein or transcriptional factor. | 0.404 |
FAM3A | HEATR1 | ENSP00000320521 | ENSP00000355541 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | HEAT repeat-containing protein 1, N-terminally processed; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I; Belongs to the HEATR1/UTP10 family. | 0.442 |
FAM3A | SNX15 | ENSP00000320521 | ENSP00000366452 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Sorting nexin-15; May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN. | 0.779 |
FAM3A | UNC45A | ENSP00000320521 | ENSP00000407487 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Protein unc-45 homolog A; Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity). | 0.478 |
FAM3A | UNC45B | ENSP00000320521 | ENSP00000268876 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | Protein unc-45 homolog B; Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development. | 0.425 |
FAM3A | WDR13 | ENSP00000320521 | ENSP00000365919 | Protein FAM3A; May act as a defensin against invading fungal microorganisms; Belongs to the FAM3 family. | WD repeat domain 13. | 0.543 |