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OPN1MW protein (human) - STRING interaction network
"OPN1MW" - Opsin 1 (cone pigments), medium-wave-sensitive in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPN1MWOpsin 1 (cone pigments), medium-wave-sensitive; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal (364 aa)    
Predicted Functional Partners:
TEX28
Testis expressed 28 (410 aa)
           
  0.832
GOLGB1
Golgin B1; May participate in forming intercisternal cross-bridges of the Golgi complex (3259 aa)
           
  0.687
ARR3
Arrestin 3, retinal (X-arrestin); May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins (388 aa)
     
 
  0.633
GNAT2
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase (354 aa)
     
 
  0.616
ARL6
ADP-ribosylation factor-like 6; Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed-20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed-22072986). May regulate cilia assembly an [...] (186 aa)
       
 
  0.503
GNAT1
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase (350 aa)
     
 
  0.493
TKTL1
Transketolase-like 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (596 aa)
           
  0.483
TNFRSF17
Tumor necrosis factor receptor superfamily, member 17; Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (184 aa)
           
  0.463
USP32
Ubiquitin specific peptidase 32 (1604 aa)
           
  0.446
PDE6C
Phosphodiesterase 6C, cGMP-specific, cone, alpha prime (858 aa)
     
 
  0.434
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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