HSFX1 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

HSFX1

Heat shock transcription factor family, X-linked 1. (423 aa)

Predicted Functional Partners:

PDZD4

0.472

VCX3B

0.466

ZNF41

0.449

CXorf40B

0.447

CXorf51A

0.447

VCX2

0.422

TSPYL2

0.411

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXorf40B	CXorf51A	ENSP00000359434	ENSP00000489806	Protein CXorf40B.	Uncharacterized protein CXorf51A; Chromosome X open reading frame 51A.	0.646
CXorf40B	HSFX1	ENSP00000359434	ENSP00000359444	Protein CXorf40B.	Heat shock transcription factor family, X-linked 1.	0.447
CXorf51A	CXorf40B	ENSP00000489806	ENSP00000359434	Uncharacterized protein CXorf51A; Chromosome X open reading frame 51A.	Protein CXorf40B.	0.646
CXorf51A	HSFX1	ENSP00000489806	ENSP00000359444	Uncharacterized protein CXorf51A; Chromosome X open reading frame 51A.	Heat shock transcription factor family, X-linked 1.	0.447
HSFX1	CXorf40B	ENSP00000359444	ENSP00000359434	Heat shock transcription factor family, X-linked 1.	Protein CXorf40B.	0.447
HSFX1	CXorf51A	ENSP00000359444	ENSP00000489806	Heat shock transcription factor family, X-linked 1.	Uncharacterized protein CXorf51A; Chromosome X open reading frame 51A.	0.447
HSFX1	PDZD4	ENSP00000359444	ENSP00000377355	Heat shock transcription factor family, X-linked 1.	PDZ domain containing 4.	0.472
HSFX1	TSPYL2	ENSP00000359444	ENSP00000364591	Heat shock transcription factor family, X-linked 1.	Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.	0.411
HSFX1	VCX2	ENSP00000359444	ENSP00000321309	Heat shock transcription factor family, X-linked 1.	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.	0.422
HSFX1	VCX3B	ENSP00000359444	ENSP00000370420	Heat shock transcription factor family, X-linked 1.	Variable charge X-linked protein 3B; May mediate a process in spermatogenesis or may play a role in sex ratio distortion.	0.466
HSFX1	ZNF41	ENSP00000359444	ENSP00000366265	Heat shock transcription factor family, X-linked 1.	Zinc finger protein 41; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.449
PDZD4	HSFX1	ENSP00000377355	ENSP00000359444	PDZ domain containing 4.	Heat shock transcription factor family, X-linked 1.	0.472
TSPYL2	HSFX1	ENSP00000364591	ENSP00000359444	Testis-specific Y-encoded-like protein 2; Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.	Heat shock transcription factor family, X-linked 1.	0.411
VCX2	HSFX1	ENSP00000321309	ENSP00000359444	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.	Heat shock transcription factor family, X-linked 1.	0.422
VCX3B	HSFX1	ENSP00000370420	ENSP00000359444	Variable charge X-linked protein 3B; May mediate a process in spermatogenesis or may play a role in sex ratio distortion.	Heat shock transcription factor family, X-linked 1.	0.466
ZNF41	HSFX1	ENSP00000366265	ENSP00000359444	Zinc finger protein 41; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	Heat shock transcription factor family, X-linked 1.	0.449