node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD16A | C6orf47 | ENSP00000379282 | ENSP00000365076 | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | 0.488 |
ABHD16A | GPANK1 | ENSP00000379282 | ENSP00000365071 | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | G-patch domain and ankyrin repeats 1. | 0.659 |
ABHD16A | LY6G5B | ENSP00000379282 | ENSP00000365024 | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | Lymphocyte antigen 6 family member G5B. | 0.538 |
ABHD16A | LY6G5C | ENSP00000379282 | ENSP00000372724 | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation. | 0.617 |
ABHD16A | PRRC2A | ENSP00000379282 | ENSP00000365201 | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing. | 0.755 |
ABT1 | GPANK1 | ENSP00000274849 | ENSP00000365071 | Activator of basal transcription 1; Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity); Belongs to the ESF2/ABP1 family. | G-patch domain and ankyrin repeats 1. | 0.519 |
ALDH18A1 | GPANK1 | ENSP00000360268 | ENSP00000365071 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. | G-patch domain and ankyrin repeats 1. | 0.495 |
ALDH18A1 | TARS2 | ENSP00000360268 | ENSP00000358060 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. | Threonine--tRNA ligase, mitochondrial; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain. | 0.572 |
ALDH18A1 | ZNF326 | ENSP00000360268 | ENSP00000340796 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. | DBIRD complex subunit ZNF326; Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro. | 0.525 |
APOM | GPANK1 | ENSP00000365081 | ENSP00000365071 | Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1- phosphate, myristic acid, palmitic acid and stearic acid, retinol, all- trans-retinoic acid and 9-cis-retinoic acid. | G-patch domain and ankyrin repeats 1. | 0.967 |
C6orf47 | ABHD16A | ENSP00000365076 | ENSP00000379282 | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | 0.488 |
C6orf47 | GPANK1 | ENSP00000365076 | ENSP00000365071 | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | G-patch domain and ankyrin repeats 1. | 0.669 |
C6orf47 | LY6G5C | ENSP00000365076 | ENSP00000372724 | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | Lymphocyte antigen 6 complex locus protein G5c; May have a role in hematopoietic cell differentiation. | 0.574 |
C6orf47 | PRRC2A | ENSP00000365076 | ENSP00000365201 | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing. | 0.453 |
GPANK1 | ABHD16A | ENSP00000365071 | ENSP00000379282 | G-patch domain and ankyrin repeats 1. | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS) (By similarity). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes (By similarity). Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). | 0.659 |
GPANK1 | ABT1 | ENSP00000365071 | ENSP00000274849 | G-patch domain and ankyrin repeats 1. | Activator of basal transcription 1; Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity); Belongs to the ESF2/ABP1 family. | 0.519 |
GPANK1 | ALDH18A1 | ENSP00000365071 | ENSP00000360268 | G-patch domain and ankyrin repeats 1. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine. | 0.495 |
GPANK1 | APOM | ENSP00000365071 | ENSP00000365081 | G-patch domain and ankyrin repeats 1. | Apolipoprotein M; Probably involved in lipid transport. Can bind sphingosine-1- phosphate, myristic acid, palmitic acid and stearic acid, retinol, all- trans-retinoic acid and 9-cis-retinoic acid. | 0.967 |
GPANK1 | C6orf47 | ENSP00000365071 | ENSP00000365076 | G-patch domain and ankyrin repeats 1. | Uncharacterized protein C6orf47; Chromosome 6 open reading frame 47. | 0.669 |
GPANK1 | LY6G5B | ENSP00000365071 | ENSP00000365024 | G-patch domain and ankyrin repeats 1. | Lymphocyte antigen 6 family member G5B. | 0.591 |