node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANOS1 | FAM9A | ENSP00000262648 | ENSP00000440163 | Anosmin-1; Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells. | Protein FAM9A; Family with sequence similarity 9 member A. | 0.571 |
ARSF | FAM9A | ENSP00000370519 | ENSP00000440163 | Arylsulfatase F. | Protein FAM9A; Family with sequence similarity 9 member A. | 0.614 |
CPXCR1 | FAM9A | ENSP00000276127 | ENSP00000440163 | CPX chromosome region candidate 1. | Protein FAM9A; Family with sequence similarity 9 member A. | 0.502 |
FAM9A | ANOS1 | ENSP00000440163 | ENSP00000262648 | Protein FAM9A; Family with sequence similarity 9 member A. | Anosmin-1; Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells. | 0.571 |
FAM9A | ARSF | ENSP00000440163 | ENSP00000370519 | Protein FAM9A; Family with sequence similarity 9 member A. | Arylsulfatase F. | 0.614 |
FAM9A | CPXCR1 | ENSP00000440163 | ENSP00000276127 | Protein FAM9A; Family with sequence similarity 9 member A. | CPX chromosome region candidate 1. | 0.502 |
FAM9A | MLLT3 | ENSP00000440163 | ENSP00000369695 | Protein FAM9A; Family with sequence similarity 9 member A. | Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...] | 0.452 |
FAM9A | NAF1 | ENSP00000440163 | ENSP00000274054 | Protein FAM9A; Family with sequence similarity 9 member A. | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. | 0.480 |
FAM9A | NAP1L3 | ENSP00000440163 | ENSP00000362171 | Protein FAM9A; Family with sequence similarity 9 member A. | Nucleosome assembly protein 1 like 3. | 0.456 |
FAM9A | NOLC1 | ENSP00000440163 | ENSP00000385410 | Protein FAM9A; Family with sequence similarity 9 member A. | Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly [...] | 0.444 |
FAM9A | OGFOD1 | ENSP00000440163 | ENSP00000457258 | Protein FAM9A; Family with sequence similarity 9 member A. | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family. | 0.641 |
FAM9A | SHROOM2 | ENSP00000440163 | ENSP00000370299 | Protein FAM9A; Family with sequence similarity 9 member A. | Protein Shroom2; May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity). Belongs to the shroom family. | 0.474 |
FAM9A | SYCP3 | ENSP00000440163 | ENSP00000376658 | Protein FAM9A; Family with sequence similarity 9 member A. | Synaptonemal complex protein 3; Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility. Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). Belongs to the XLR/SYCP3 family. | 0.905 |
MLLT3 | FAM9A | ENSP00000369695 | ENSP00000440163 | Protein AF-9; Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylate [...] | Protein FAM9A; Family with sequence similarity 9 member A. | 0.452 |
NAF1 | FAM9A | ENSP00000274054 | ENSP00000440163 | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. | Protein FAM9A; Family with sequence similarity 9 member A. | 0.480 |
NAF1 | NOLC1 | ENSP00000274054 | ENSP00000385410 | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. | Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly [...] | 0.714 |
NAP1L3 | FAM9A | ENSP00000362171 | ENSP00000440163 | Nucleosome assembly protein 1 like 3. | Protein FAM9A; Family with sequence similarity 9 member A. | 0.456 |
NOLC1 | FAM9A | ENSP00000385410 | ENSP00000440163 | Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly [...] | Protein FAM9A; Family with sequence similarity 9 member A. | 0.444 |
NOLC1 | NAF1 | ENSP00000385410 | ENSP00000274054 | Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly [...] | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. | 0.714 |
NOLC1 | OGFOD1 | ENSP00000385410 | ENSP00000457258 | Nucleolar and coiled-body phosphoprotein 1; Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly [...] | Prolyl 3-hydroxylase OGFOD1; Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro- 62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation; Belongs to the TPA1 family. | 0.438 |