node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRWD3 | ZNF891 | ENSP00000362372 | ENSP00000437590 | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.427 |
CEP250 | ZNF891 | ENSP00000380661 | ENSP00000437590 | Centrosome-associated protein CEP250; May be involved in ciliogenesis. Probably plays an important role in centrosome cohesion during interphase. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.411 |
CTAGE8 | FAM86B2 | ENSP00000417289 | ENSP00000262365 | CTAGE family member 8. | Putative protein N-methyltransferase FAM86B2; Family with sequence similarity 86 member B2. | 0.446 |
CTAGE8 | ZNF891 | ENSP00000417289 | ENSP00000437590 | CTAGE family member 8. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.503 |
DPH5 | ZNF891 | ENSP00000359127 | ENSP00000437590 | Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.437 |
FAM86B2 | CTAGE8 | ENSP00000262365 | ENSP00000417289 | Putative protein N-methyltransferase FAM86B2; Family with sequence similarity 86 member B2. | CTAGE family member 8. | 0.446 |
FAM86B2 | ZNF891 | ENSP00000262365 | ENSP00000437590 | Putative protein N-methyltransferase FAM86B2; Family with sequence similarity 86 member B2. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.448 |
FBXO33 | ZNF891 | ENSP00000298097 | ENSP00000437590 | F-box only protein 33; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1 (By similarity). | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.479 |
GLYCTK | ZNF891 | ENSP00000389175 | ENSP00000437590 | Glycerate kinase; Belongs to the glycerate kinase type-2 family. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.434 |
USP27X | ZNF891 | ENSP00000483631 | ENSP00000437590 | Ubiquitin carboxyl-terminal hydrolase 27; Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK- degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.404 |
WNK3 | ZNF891 | ENSP00000346667 | ENSP00000437590 | Serine/threonine-protein kinase WNK3; Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the ce [...] | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.404 |
ZCCHC2 | ZNF891 | ENSP00000269499 | ENSP00000437590 | Zinc finger CCHC-type containing 2. | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.485 |
ZNF891 | BRWD3 | ENSP00000437590 | ENSP00000362372 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | 0.427 |
ZNF891 | CEP250 | ENSP00000437590 | ENSP00000380661 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Centrosome-associated protein CEP250; May be involved in ciliogenesis. Probably plays an important role in centrosome cohesion during interphase. | 0.411 |
ZNF891 | CTAGE8 | ENSP00000437590 | ENSP00000417289 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | CTAGE family member 8. | 0.503 |
ZNF891 | DPH5 | ENSP00000437590 | ENSP00000359127 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Diphthine methyl ester synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.437 |
ZNF891 | FAM86B2 | ENSP00000437590 | ENSP00000262365 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Putative protein N-methyltransferase FAM86B2; Family with sequence similarity 86 member B2. | 0.448 |
ZNF891 | FBXO33 | ENSP00000437590 | ENSP00000298097 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | F-box only protein 33; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1 (By similarity). | 0.479 |
ZNF891 | GLYCTK | ENSP00000437590 | ENSP00000389175 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Glycerate kinase; Belongs to the glycerate kinase type-2 family. | 0.434 |
ZNF891 | USP27X | ENSP00000437590 | ENSP00000483631 | Zinc finger protein 891; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ubiquitin carboxyl-terminal hydrolase 27; Deubiquitinase that can reduce the levels of BCL2L11/BIM ubiquitination and stabilize BCL2L11 in response to the RAF-MAPK- degradation signal. By acting on BCL2L11 levels, may counteract the anti-apoptotic effects of MAPK activity. | 0.404 |