STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAGEB16Melanoma-associated antigen B16; MAGE family member B16. (324 aa)    
Predicted Functional Partners:
MAGEA4
Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
  
 
0.641
FAM209A
Protein FAM209A; Family with sequence similarity 209 member A.
      
 0.625
C12orf40
Uncharacterized protein C12orf40; Chromosome 12 open reading frame 40.
      
 0.614
C9orf131
Uncharacterized protein C9orf131; Chromosome 9 open reading frame 131.
    
 
 0.606
OR2L8
Olfactory receptor 2L8; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.588
C9orf43
Uncharacterized protein C9orf43; Chromosome 9 open reading frame 43.
      
 0.584
SLC22A24
Steroid transmembrane transporter SLC22A24; Steroid transmembrane transporter that functions in the reabsorption of conjugated steroids in the kidney and is involved in steroid homeostasis. [Isoform 3]: Lack of transporter activity.
   
 
 0.583
TMCO5A
Transmembrane and coiled-coil domains 5A; Belongs to the TMCO5 family.
      
 0.566
ZFAND4
Zinc finger AN1-type containing 4.
      
 0.560
PKDREJ
Polycystic kidney disease and receptor for egg jelly-related protein; May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm; Belongs to the polycystin family.
    
 
 0.555
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.