node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BUD31 | CDC40 | ENSP00000386023 | ENSP00000357928 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | 0.999 |
BUD31 | CRNKL1 | ENSP00000386023 | ENSP00000366557 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. | 0.999 |
BUD31 | DHX15 | ENSP00000386023 | ENSP00000336741 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | 0.993 |
BUD31 | EFTUD2 | ENSP00000386023 | ENSP00000392094 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.999 |
BUD31 | PRPF8 | ENSP00000386023 | ENSP00000460348 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | 0.999 |
BUD31 | SNRPA1 | ENSP00000386023 | ENSP00000254193 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. Belongs to the U2 small nuclear ribonucleoprotein A family. | 0.999 |
BUD31 | TFIP11 | ENSP00000386023 | ENSP00000384421 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] | 0.972 |
BUD31 | XAB2 | ENSP00000386023 | ENSP00000351137 | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | Pre-mRNA-splicing factor SYF1; Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Belongs to the crooked-neck family. | 0.999 |
CDC40 | BUD31 | ENSP00000357928 | ENSP00000386023 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | 0.999 |
CDC40 | CRNKL1 | ENSP00000357928 | ENSP00000366557 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. | 0.999 |
CDC40 | DHX15 | ENSP00000357928 | ENSP00000336741 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | 0.999 |
CDC40 | EFTUD2 | ENSP00000357928 | ENSP00000392094 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.999 |
CDC40 | GCFC2 | ENSP00000357928 | ENSP00000318690 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | GC-rich sequence DNA-binding factor 2; Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons; Belongs to the GCF family. | 0.829 |
CDC40 | PRPF8 | ENSP00000357928 | ENSP00000460348 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | 0.999 |
CDC40 | SNRPA1 | ENSP00000357928 | ENSP00000254193 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. Belongs to the U2 small nuclear ribonucleoprotein A family. | 0.999 |
CDC40 | TFIP11 | ENSP00000357928 | ENSP00000384421 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] | 0.981 |
CDC40 | XAB2 | ENSP00000357928 | ENSP00000351137 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Pre-mRNA-splicing factor SYF1; Involved in pre-mRNA splicing as component of the spliceosome. Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Belongs to the crooked-neck family. | 0.999 |
CRNKL1 | BUD31 | ENSP00000366557 | ENSP00000386023 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. | Protein BUD31 homolog; Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity. | 0.999 |
CRNKL1 | CDC40 | ENSP00000366557 | ENSP00000357928 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | 0.999 |
CRNKL1 | DHX15 | ENSP00000366557 | ENSP00000336741 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process. Belongs to the crooked-neck family. | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | 0.988 |