node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MUC12 | MUC13 | ENSP00000441929 | ENSP00000485028 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.980 |
MUC12 | MUC15 | ENSP00000441929 | ENSP00000431983 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.950 |
MUC12 | MUC17 | ENSP00000441929 | ENSP00000302716 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces. | 0.929 |
MUC12 | MUC19 | ENSP00000441929 | ENSP00000495398 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-19; May function in ocular mucus homeostasis. | 0.895 |
MUC12 | MUC2 | ENSP00000441929 | ENSP00000494061 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.951 |
MUC12 | MUC20 | ENSP00000441929 | ENSP00000414350 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.938 |
MUC12 | MUC3A | ENSP00000441929 | ENSP00000368771 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-3A; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. | 0.826 |
MUC12 | MUC5AC | ENSP00000441929 | ENSP00000485659 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). | 0.932 |
MUC12 | MUC5B | ENSP00000441929 | ENSP00000436812 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.936 |
MUC12 | MUC7 | ENSP00000441929 | ENSP00000407422 | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. | 0.902 |
MUC13 | MUC12 | ENSP00000485028 | ENSP00000441929 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-12; Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. | 0.980 |
MUC13 | MUC15 | ENSP00000485028 | ENSP00000431983 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.940 |
MUC13 | MUC17 | ENSP00000485028 | ENSP00000302716 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-17; Probably plays a role in maintaining homeostasis on mucosal surfaces. | 0.969 |
MUC13 | MUC19 | ENSP00000485028 | ENSP00000495398 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-19; May function in ocular mucus homeostasis. | 0.872 |
MUC13 | MUC2 | ENSP00000485028 | ENSP00000494061 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.961 |
MUC13 | MUC20 | ENSP00000485028 | ENSP00000414350 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.949 |
MUC13 | MUC3A | ENSP00000485028 | ENSP00000368771 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-3A; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. | 0.920 |
MUC13 | MUC5AC | ENSP00000485028 | ENSP00000485659 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-5AC; Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD). | 0.946 |
MUC13 | MUC5B | ENSP00000485028 | ENSP00000436812 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.926 |
MUC13 | MUC7 | ENSP00000485028 | ENSP00000407422 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. | 0.942 |