node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLVRA | C7orf25 | ENSP00000385757 | ENSP00000413029 | Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.437 |
C7orf25 | BLVRA | ENSP00000413029 | ENSP00000385757 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Biliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. | 0.437 |
C7orf25 | CXorf58 | ENSP00000413029 | ENSP00000368511 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58. | 0.666 |
C7orf25 | FAM204A | ENSP00000413029 | ENSP00000358183 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Protein FAM204A; Family with sequence similarity 204 member A. | 0.478 |
C7orf25 | FAM220A | ENSP00000413029 | ENSP00000317289 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Protein FAM220A; May negatively regulate STAT3. | 0.433 |
C7orf25 | LANCL2 | ENSP00000413029 | ENSP00000254770 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. | 0.422 |
C7orf25 | PSMA2 | ENSP00000413029 | ENSP00000223321 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Proteasome subunit alpha type-2; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] | 0.705 |
C7orf25 | SEC61G | ENSP00000413029 | ENSP00000388337 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Protein transport protein Sec61 subunit gamma; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER); Belongs to the SecE/SEC61-gamma family. | 0.490 |
C7orf25 | SMLR1 | ENSP00000413029 | ENSP00000456026 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Small leucine rich protein 1. | 0.580 |
C7orf25 | VOPP1 | ENSP00000413029 | ENSP00000285279 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family. | 0.499 |
C7orf25 | WDR83 | ENSP00000413029 | ENSP00000402653 | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | WD repeat domain-containing protein 83; Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activato [...] | 0.551 |
CXorf58 | C7orf25 | ENSP00000368511 | ENSP00000413029 | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58. | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.666 |
CXorf58 | SMLR1 | ENSP00000368511 | ENSP00000456026 | Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58. | Small leucine rich protein 1. | 0.770 |
FAM204A | C7orf25 | ENSP00000358183 | ENSP00000413029 | Protein FAM204A; Family with sequence similarity 204 member A. | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.478 |
FAM220A | C7orf25 | ENSP00000317289 | ENSP00000413029 | Protein FAM220A; May negatively regulate STAT3. | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.433 |
LANCL2 | C7orf25 | ENSP00000254770 | ENSP00000413029 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.422 |
LANCL2 | SEC61G | ENSP00000254770 | ENSP00000388337 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. | Protein transport protein Sec61 subunit gamma; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER); Belongs to the SecE/SEC61-gamma family. | 0.639 |
LANCL2 | VOPP1 | ENSP00000254770 | ENSP00000285279 | LanC-like protein 2; Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes. | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family. | 0.682 |
PSMA2 | C7orf25 | ENSP00000223321 | ENSP00000413029 | Proteasome subunit alpha type-2; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] | UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family. | 0.705 |
PSMA2 | SEC61G | ENSP00000223321 | ENSP00000388337 | Proteasome subunit alpha type-2; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] | Protein transport protein Sec61 subunit gamma; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER); Belongs to the SecE/SEC61-gamma family. | 0.609 |