STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMIM7Small integral membrane protein 7. (103 aa)    
Predicted Functional Partners:
COG3
Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.
   
 
 0.731
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.
   
 
 0.673
TMEM38A
Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
      
 0.668
COG8
Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
   
 
 0.618
COG2
Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.
   
 
 0.588
ODF3L2
Outer dense fiber of sperm tails 3 like 2.
      
 0.582
H3BMQ9_HUMAN
Uncharacterized protein.
    
 
 0.531
H3BUN2_HUMAN
Uncharacterized protein.
    
 
 0.531
SPCS1
Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.
   
    0.517
GABPB2
GA-binding protein subunit beta-2; May function as transcription factor capable of interacting with purine rich repeats (GA repeats).
   
  
 0.499
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.