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PCDHGA1 protein (human) - STRING interaction network
"PCDHGA1" - Protocadherin gamma-A1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
PCDHGA1Protocadherin gamma-A1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (931 aa)    
Predicted Functional Partners:
OR4K14
Olfactory receptor 4K14; Odorant receptor; Olfactory receptors, family 4 (310 aa)
           
  0.578
OR4N5
Olfactory receptor 4N5; Odorant receptor; Olfactory receptors, family 4 (308 aa)
           
  0.545
C11orf80
Type 2 DNA topoisomerase 6 subunit B-like; Isoform 3- Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles (572 aa)
           
  0.503
ATP8A2
Phospholipid-transporting ATPase IB; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes, the ATP8A2-TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). [...] (1188 aa)
           
  0.455
PABPC5
Polyadenylate-binding protein 5; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity); RNA binding motif containing (382 aa)
           
  0.438
TMEM132C
Transmembrane protein 132C; Protein phosphatase 1 regulatory subunits (1108 aa)
           
  0.433
ZNF473
Zinc finger protein 473; Involved in histone 3’-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3’-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases; Zinc fingers C2H2-type (871 aa)
       
 
  0.431
IZUMO2
Izumo sperm-egg fusion protein 2; IZUMO family member 2 (221 aa)
           
  0.426
KLHL4
Kelch-like protein 4; Kelch like family member 4; BTB domain containing (720 aa)
     
   
  0.423
CCDC85A
Coiled-coil domain containing 85A; Belongs to the CCDC85 family (553 aa)
           
  0.419
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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