STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDZD9PDZ domain containing 9. (204 aa)    
Predicted Functional Partners:
VWA3A
Von Willebrand factor A domain containing 3A.
   
  
 0.758
FAM222B
Protein FAM222B; Family with sequence similarity 222 member B; Belongs to the FAM222 family.
      
 0.641
MISP3
Uncharacterized protein MISP3; MISP family member 3; Belongs to the MISP family.
      
 0.623
CCDC189
Coiled-coil domain containing 189.
      
 0.597
OR2K2
Olfactory receptor 2K2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.558
OR51D1
Olfactory receptor 51D1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.533
TMCO6
Transmembrane and coiled-coil domains 6.
      
 0.513
POLR3E
DNA-directed RNA polymerase III subunit RPC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA th [...]
      
 0.511
MPP4
MAGUK p55 subfamily member 4; May play a role in retinal photoreceptors development.
   
  
 0.511
C16orf54
Transmembrane protein C16orf54; Chromosome 16 open reading frame 54.
      
 0.491
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.