node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDYL2 | CLEC3A | ENSP00000476295 | ENSP00000499168 | Chromodomain Y like 2. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.443 |
CHRDL2 | CLEC3A | ENSP00000263671 | ENSP00000499168 | Chordin-like protein 2; May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation (By similarity). Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.517 |
CLEC1B | CLEC3A | ENSP00000298527 | ENSP00000499168 | C-type lectin domain family 1 member B; C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2. (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.531 |
CLEC2B | CLEC3A | ENSP00000228438 | ENSP00000499168 | C-type lectin domain family 2 member B. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.512 |
CLEC3A | CDYL2 | ENSP00000499168 | ENSP00000476295 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Chromodomain Y like 2. | 0.443 |
CLEC3A | CHRDL2 | ENSP00000499168 | ENSP00000263671 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Chordin-like protein 2; May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation (By similarity). Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation. | 0.517 |
CLEC3A | CLEC1B | ENSP00000499168 | ENSP00000298527 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | C-type lectin domain family 1 member B; C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN. After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2. (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. | 0.531 |
CLEC3A | CLEC2B | ENSP00000499168 | ENSP00000228438 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | C-type lectin domain family 2 member B. | 0.512 |
CLEC3A | CYTL1 | ENSP00000499168 | ENSP00000303550 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Cytokine-like protein 1; Cytokine like 1. | 0.487 |
CLEC3A | LAMA1 | ENSP00000499168 | ENSP00000374309 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Laminin subunit alpha-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.669 |
CLEC3A | MMP7 | ENSP00000499168 | ENSP00000260227 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. | 0.673 |
CLEC3A | RNASEH1 | ENSP00000499168 | ENSP00000313350 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II ; Belongs to the RNase H family. | 0.511 |
CLEC3A | VAT1L | ENSP00000499168 | ENSP00000303129 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | Synaptic vesicle membrane protein VAT-1 homolog-like; Vesicle amine transport 1 like; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. | 0.646 |
CLEC3A | WWOX | ENSP00000499168 | ENSP00000457230 | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | WW domain-containing oxidoreductase; Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm. | 0.463 |
CYTL1 | CLEC3A | ENSP00000303550 | ENSP00000499168 | Cytokine-like protein 1; Cytokine like 1. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.487 |
LAMA1 | CLEC3A | ENSP00000374309 | ENSP00000499168 | Laminin subunit alpha-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.669 |
LAMA1 | MMP7 | ENSP00000374309 | ENSP00000260227 | Laminin subunit alpha-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. | 0.426 |
MMP7 | CLEC3A | ENSP00000260227 | ENSP00000499168 | Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.673 |
MMP7 | LAMA1 | ENSP00000260227 | ENSP00000374309 | Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. | Laminin subunit alpha-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.426 |
RNASEH1 | CLEC3A | ENSP00000313350 | ENSP00000499168 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II ; Belongs to the RNase H family. | C-type lectin domain family 3 member A; Promotes cell adhesion to laminin-332 and fibronectin. | 0.511 |