HLA-DQB2 protein (Canis lupus familiaris) - STRING interaction network

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gene neighborhood

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textmining

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Score

HLA-DQB2

Major histocompatibility complex, class II, DQ beta 1. (205 aa)

Predicted Functional Partners:

DLA-DRA

0.987

CD4

0.971

DLA-DOA

0.935

DLA-DQA1

0.932

CD247

0.910

CD74

0.903

HLA-DQB1

0.901

E2R820_CANLF

0.851

HCRT

0.813

DLA-DMA

0.786

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	CD4	ENSCAFP00000041707	ENSCAFP00000063394	Uncharacterized protein.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.717
CD247	DLA-DOA	ENSCAFP00000041707	ENSCAFP00000001280	Uncharacterized protein.	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.907
CD247	DLA-DQA1	ENSCAFP00000041707	ENSCAFP00000001164	Uncharacterized protein.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.543
CD247	DLA-DRA	ENSCAFP00000041707	ENSCAFP00000045482	Uncharacterized protein.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.917
CD247	E2R820_CANLF	ENSCAFP00000041707	ENSCAFP00000034736	Uncharacterized protein.	DUF1968 domain-containing protein.	0.540
CD247	HLA-DQB1	ENSCAFP00000041707	ENSCAFP00000001171	Uncharacterized protein.	Major histocompatibility complex, class II, DQ beta 2.	0.910
CD247	HLA-DQB2	ENSCAFP00000041707	ENSCAFP00000001156	Uncharacterized protein.	Major histocompatibility complex, class II, DQ beta 1.	0.910
CD4	CD247	ENSCAFP00000063394	ENSCAFP00000041707	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.717
CD4	DLA-DOA	ENSCAFP00000063394	ENSCAFP00000001280	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.910
CD4	DLA-DQA1	ENSCAFP00000063394	ENSCAFP00000001164	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.682
CD4	DLA-DRA	ENSCAFP00000063394	ENSCAFP00000045482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.984
CD4	E2R820_CANLF	ENSCAFP00000063394	ENSCAFP00000034736	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	DUF1968 domain-containing protein.	0.599
CD4	HLA-DQB1	ENSCAFP00000063394	ENSCAFP00000001171	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 2.	0.987
CD4	HLA-DQB2	ENSCAFP00000063394	ENSCAFP00000001156	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 1.	0.971
CD74	DLA-DMA	ENSCAFP00000045678	ENSCAFP00000001218	CD74 molecule.	MHC class II antigen DM alpha; Belongs to the MHC class II family.	0.782
CD74	DLA-DOA	ENSCAFP00000045678	ENSCAFP00000001280	CD74 molecule.	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.445
CD74	DLA-DQA1	ENSCAFP00000045678	ENSCAFP00000001164	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.959
CD74	DLA-DRA	ENSCAFP00000045678	ENSCAFP00000045482	CD74 molecule.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.987
CD74	HLA-DQB1	ENSCAFP00000045678	ENSCAFP00000001171	CD74 molecule.	Major histocompatibility complex, class II, DQ beta 2.	0.933
CD74	HLA-DQB2	ENSCAFP00000045678	ENSCAFP00000001156	CD74 molecule.	Major histocompatibility complex, class II, DQ beta 1.	0.903