STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXNA4Plexin A4. (1939 aa)    
Predicted Functional Partners:
NRP1
Neuropilin 1.
    
 0.990
SEMA3A
Semaphorin 3A; Belongs to the semaphorin family.
    
0.977
RND1
Rho family GTPase 1.
    
 0.939
RHOD
Ras homolog family member D.
    
 0.929
RAC2
Rac family small GTPase 2.
   
 0.920
RAC3
Uncharacterized protein.
   
 0.920
FES
Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
   
 0.912
PLXNA3
Plexin A3.
  
  
0.903
PLXNA2
Plexin A2.
  
 
 
0.901
SEMA6A
Semaphorin 6A; Belongs to the semaphorin family.
    
 
0.813
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.