STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COL21A1Collagen type XXI alpha 1 chain. (957 aa)    
Predicted Functional Partners:
COL22A1
Collagen type XXII alpha 1 chain.
  
 
0.827
COL4A6
Collagen type IV alpha 6 chain.
  
 
0.785
COL26A1
Collagen type XXVI alpha 1 chain.
     
 0.777
COL17A1
120 kDa linear IgA disease antigen homolog; The 120 kDa linear IgA disease antigen homolog is an anchoring filament component involved in dermal-epidermal cohesion.
  
  
0.742
COL8A1
Collagen type VIII alpha 1 chain.
  
0.709
STK17A
Serine/threonine kinase 17a.
    
 
 0.699
COL23A1
Collagen type XXIII alpha 1 chain.
  
  
0.692
COL25A1
Collagen type XXV alpha 1 chain.
  
  
0.686
COL24A1
Collagen type XXIV alpha 1 chain.
  
  
0.673
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
   
 0.671
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.