STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO48F-box protein 48 (141 aa)    
Predicted Functional Partners:
FBXO47
F-box protein 47
   
  
 0.808
ETAA1
ETAA1, ATR kinase activator; Ewing tumor-associated antigen 1
   
  
 0.699
LMO7
LIM domain 7
      
 0.690
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family
    
 
 0.655
PNO1
Partner of NOB1 homolog (S. cerevisiae)
      
 0.565
APLF
Aprataxin and PNKP like factor
      
 0.560
LRRC29
Uncharacterized protein; Leucine rich repeat containing 29
      
 0.559
CNRIP1
Cannabinoid receptor interacting protein 1
      
 0.559
FBXL15
F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity); Belongs to the FBXL15 family
      
 0.559
PCIF1
PDX1 C-terminal inhibiting factor 1
      
 0.551
Your Current Organism:
Canis lupus
NCBI taxonomy Id: 9612
Other names: C. lupus, Canis familiaris, Canis lupus, gray wolf, grey wolf
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