node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA1 | NR1H2 | ENSCAFP00000052429 | ENSCAFP00000004950 | ATP binding cassette subfamily A member 1. | Nuclear receptor subfamily 1 group H member 2. | 0.901 |
ABCA1 | NR1H3 | ENSCAFP00000052429 | ENSCAFP00000012970 | ATP binding cassette subfamily A member 1. | Nuclear receptor subfamily 1 group H member 3. | 0.670 |
ABCA1 | RXRA | ENSCAFP00000052429 | ENSCAFP00000058322 | ATP binding cassette subfamily A member 1. | Retinoid X receptor alpha. | 0.857 |
MED1 | NCOA1 | ENSCAFP00000024203 | ENSCAFP00000006049 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.762 |
MED1 | NCOA2 | ENSCAFP00000024203 | ENSCAFP00000065782 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator 2. | 0.544 |
MED1 | NCOR1 | ENSCAFP00000024203 | ENSCAFP00000053648 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.601 |
MED1 | NCOR2 | ENSCAFP00000024203 | ENSCAFP00000010374 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.729 |
MED1 | NR1H2 | ENSCAFP00000024203 | ENSCAFP00000004950 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 2. | 0.742 |
MED1 | NR1H3 | ENSCAFP00000024203 | ENSCAFP00000012970 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 3. | 0.742 |
MED1 | RXRA | ENSCAFP00000024203 | ENSCAFP00000058322 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.893 |
MED1 | RXRB | ENSCAFP00000024203 | ENSCAFP00000001304 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor RXR-beta; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE); Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.841 |
NCOA1 | MED1 | ENSCAFP00000006049 | ENSCAFP00000024203 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.762 |
NCOA1 | NCOA2 | ENSCAFP00000006049 | ENSCAFP00000065782 | Nuclear receptor coactivator. | Nuclear receptor coactivator 2. | 0.983 |
NCOA1 | NCOR1 | ENSCAFP00000006049 | ENSCAFP00000053648 | Nuclear receptor coactivator. | Nuclear receptor corepressor 1. | 0.746 |
NCOA1 | NCOR2 | ENSCAFP00000006049 | ENSCAFP00000010374 | Nuclear receptor coactivator. | Nuclear receptor corepressor 2. | 0.740 |
NCOA1 | NR1H2 | ENSCAFP00000006049 | ENSCAFP00000004950 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 2. | 0.858 |
NCOA1 | NR1H3 | ENSCAFP00000006049 | ENSCAFP00000012970 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 3. | 0.858 |
NCOA1 | RXRA | ENSCAFP00000006049 | ENSCAFP00000058322 | Nuclear receptor coactivator. | Retinoid X receptor alpha. | 0.962 |
NCOA1 | RXRB | ENSCAFP00000006049 | ENSCAFP00000001304 | Nuclear receptor coactivator. | Retinoic acid receptor RXR-beta; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE); Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.851 |
NCOA2 | MED1 | ENSCAFP00000065782 | ENSCAFP00000024203 | Nuclear receptor coactivator 2. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.544 |